Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215364 | 0.76 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL30770947 | 0.76 | KMO (0.44) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL12845094 | 0.74 | MAPT (0.55) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL17311194 | 0.71 | XDH (0.46) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL1094404 | 0.71 | ALDH1A1 (0.56) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL17347250 | 0.70 | SRC (0.38) | MAPTALDH1A1CYP3A4HSD17B10MEN1 | |
| SCHEMBL31692856 | 0.70 | HNF4A (0.54) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL30412897 | 0.69 | ALDH1A1 (0.55) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL4988910 | 0.69 | HSD17B10 (0.55) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL5610655 | 0.69 | ALOX15 (0.55) | MAPTALDH1A1KDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580379-B2 | Xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-02-28 | — | — | US | disclosed |
| US-9580379-B2 | Xanthine oxidase inhibitors and methods of use | BAYLOR COLLEGE OF MEDICINE (US) | 2017-02-28 | — | — | US | disclosed |
| WO-2015191635-A2 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE (US) | 2015-12-17 | — | — | WO | disclosed |
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE | 2015-12-10 | — | — | US | disclosed |
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | BAYLOR COLLEGE OF MEDICINE | 2015-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353471-A1 | XANTHINE OXIDASE INHIBITORS AND METHODS OF USE | XDH, PNPO, AOX1 | MAPT 3718/4885ALDH1A1 408/4885KDM4E 3137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.