Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ASAH1 | Q13510 | 6/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133464 | 0.84 | ALDH1A1 (0.57) | KMT2APKMASAH1NR1H2L3MBTL1 | |
| SCHEMBL11702245 | 0.83 | L3MBTL1 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7249675 | 0.83 | NR1H2 (0.43) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL25168045 | 0.82 | L3MBTL1 (0.46) | MEN1KMT2AKDM4EPKMNR1H2 | |
| SCHEMBL25736832 | 0.82 | L3MBTL1 (0.46) | KMT2AKDM4EPKMNR1H2L3MBTL1 | |
| SCHEMBL3447293 | 0.82 | CNR2 (0.46) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4698252 | 0.82 | SMN1; SMN2 (0.47) | SMN1; SMN2KMT2AKDM4EPKMLMNA | |
| SCHEMBL2340371 | 0.81 | L3MBTL1 (0.45) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14838247 | 0.81 | CYP1A2 (0.47) | MEN1KMT2AKDM4ELMNAPOLB | |
| SCHEMBL2724339 | 0.81 | NR1H2 (0.40) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384100-A | Carbendazim hapten and artificial antigen as well as preparation methods and application thereof | 河南农业大学 | 2024-01-12 | — | — | CN | claimed |
| US-12630562-B2 | Piperidylurea compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| US-20260042777-A1 | PIPERIDYLUREA COMPOUNDS AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2026-02-12 | — | — | US | disclosed |
| CN-117384100-A | Carbendazim hapten and artificial antigen as well as preparation methods and application thereof | 河南农业大学 | 2024-01-12 | — | — | CN | disclosed |
| US-20180319955-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORPORATION (JP) | 2018-11-08 | — | — | US | disclosed |
| US-10053553-B2 | Rubber composition, and pneumatic tire using same | BRIDGESTONE CORPORATION (JP) | 2018-08-21 | — | — | US | disclosed |
| EP-2960284-B1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2018-08-01 | — | — | EP | disclosed |
| CN-104955890-B | Rubber composition and use its pneumatic tire | 株式会社普利司通 | 2017-11-28 | — | — | CN | disclosed |
| EP-2960284-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2015-12-30 | — | — | EP | disclosed |
| US-20150361248-A1 | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2015-12-17 | — | — | US | disclosed |
| CN-104955890-A | RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP | 2015-09-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630562-B2 | Piperidylurea compounds and methods of use thereof | CLIC1, HCCS, CNR1 | NPC1 73/4885RAB9A 767/4885SMN1; SMN2 1154/4885 |
| US-20260042777-A1 | PIPERIDYLUREA COMPOUNDS AND METHODS OF USE THEREOF | CBR1, CLIC1, RER1 | NPC1 134/4885RAB9A 485/4885SMN1; SMN2 1375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.