SCHEMBL17344178

SCHEMBL17344178

C[PH](=O)c1ccc(S(=O)(=O)OCC(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
PTGS2 P35354 2/20 0.33
BCHE P06276 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17348014 0.82 CA1 (0.33) CA2CA1CA9PTGS2
SCHEMBL68796 0.80 GAA (0.43) CA2CA1CA9BCHEACHE
SCHEMBL21595326 0.78 PTGS2 (0.49) CA2CA1CA9PTGS2BCHE
SCHEMBL15895016 0.76 PLCG1 (0.44) CA2CA1CA9PTGS2
SCHEMBL2270234 0.75 CA1 (0.43) CA2CA1CA9PTGS2
SCHEMBL15895019 0.73 CA2 (0.38) CA2CA1CA9PTGS2
SCHEMBL14382995 0.72 TDP1 (0.46) CA2CA1CA9PTGS2
SCHEMBL14973316 0.72 CA1 (0.42) CA2CA1CA9PTGS2BCHE
SCHEMBL9040346 0.71 LMNA (0.47)
SCHEMBL14972994 0.71 MMP1 (0.35) CA2CA1CA9PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9920082-B2 Water-soluble complexing agents and corresponding lanthanide complexes CISBO BIOASSAYS (FR) 2018-03-20 US disclosed
US-20150361116-A1 NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES CISBIO BIOASSAYS (FR) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361116-A1 NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES RCC1, CLIC1, RCC2 CA2 21/4885CA1 204/4885CA9 149/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.