SCHEMBL17345241

SCHEMBL17345241

CCOCC(COc1ccc(C(c2ccc(OCC3CO3)cc2)c2ccc(OCC3CO3)cc2)cc1)OC(=O)NCCC[Si](OCC)(OCC)OCC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HPGD P15428 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
EPHX2 P34913 1/20 0.32
TP53 P04637 2/20 0.32
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
PKM P14618 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP1A2 P05177 1/20 0.32
PPARG P37231 1/20 0.32
HIF1A Q16665 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
ACACB O00763 1/20 0.31
MAPK1 P28482 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17051348 0.92 NPC1 (0.31) NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL17345248 0.90 HPGD (0.46) NPC1RAB9AHPGDSMN1; SMN2TP53
SCHEMBL16640989 0.86 MGLL (0.42) HPGDSMN1; SMN2TP53MAPTTSHR
SCHEMBL17345234 0.85 HPGD (0.47) NPC1RAB9AHPGDSMN1; SMN2EPHX2
SCHEMBL17345233 0.85 PLA2G2A (0.32) NPC1RAB9AHPGDSMN1; SMN2EPHX2
SCHEMBL17051377 0.83 MAPT (0.42) NPC1RAB9AHPGDSMN1; SMN2TP53
SCHEMBL2263171 0.81 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1BCHE
SCHEMBL19901205 0.80 MGLL (0.42) HPGDSMN1; SMN2TP53MAPTTSHR
SCHEMBL16640964 0.80 MGLL (0.47) SMN1; SMN2MGLLBCHE
SCHEMBL17345227 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732182-B2 Epoxy compound having alkoxysilyl group, method of preparing the same, composition and cured product comprising the same, and use thereof KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2017-08-15 US disclosed
US-20150361211-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD OF PREPARING THE SAME, COMPOSITION AND CURED PRODUCT COMPRISING THE SAME, AND USE THEREOF KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2015-12-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150361211-A1 EPOXY COMPOUND HAVING ALKOXYSILYL GROUP, METHOD OF PREPARING THE SAME, COMPOSITION AND CURED PRODUCT COMPRISING THE SAME, AND USE THEREOF ESD, PFAS, SCD5 NPC1 3136/4885RAB9A 3173/4885HPGD 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.