Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4306061 | 0.81 | TRPV4 (0.44) | TRPV4MCOLN3NFE2L2ALDH1A1CCR4 | |
| SCHEMBL11138757 | 0.72 | TRPV4 (0.46) | TRPV4NFE2L2KMT2AALDH1A1TDP1 | |
| SCHEMBL17355704 | 0.72 | RORC (0.40) | HSD11B1KMT2AMEN1 | |
| SCHEMBL7384413 | 0.72 | HSD11B1 (0.38) | HSD11B1TRPV4MCOLN3KMT2ATSHR | |
| SCHEMBL7804021 | 0.72 | ELANE (0.46) | HSD11B1TRPV4NFE2L2KMT2AMEN1 | |
| SCHEMBL27752732 | 0.71 | NFE2L2 (0.45) | NFE2L2ALDH1A1KCNH2 | |
| SCHEMBL350041 | 0.71 | HSD11B1 (0.50) | HSD11B1MCOLN3KMT2ATSHRMEN1 | |
| SCHEMBL27669603 | 0.70 | ALDH1A1 (0.44) | MCOLN3NFE2L2KMT2ATSHRMEN1 | |
| SCHEMBL29628473 | 0.70 | TRPV4 (0.41) | TRPV4NFE2L2KMT2ATSHRAPEX1 | |
| SCHEMBL29519135 | 0.70 | TSHR (0.53) | MCOLN3KMT2ATSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612173-A | INDOPHENOL DYE | EASTMAN KODAK COMPANY (US) | 1997-03-18 | — | — | US | disclosed |
| EP-0574090-A1 | One equivalent couplers and low pKa release dyes | EASTMAN KODAK COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |