SCHEMBL17366394

SCHEMBL17366394

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4ccc5cc(-c6ccc7c(c6)c6cnccc6n7-c6ccccc6)ccc5c4)ccc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 4/20 0.39
CYP11B2 P19099 4/20 0.39
CYP19A1 P11511 3/20 0.39
CYP17A1 P05093 1/20 0.39
MAPK10 P53779 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
HSP90AA1 P07900 1/20 0.35
MAPT P10636 1/20 0.35
ALOX5 P09917 1/20 0.35
HSD17B1 P14061 2/20 0.34
HSD17B2 P37059 2/20 0.34
TDO2 P48775 1/20 0.34
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12098380 0.95 CYP17A1 (0.42) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL12098192 0.95 ATM (0.39) MAPK10KDM4EATML3MBTL1KMT2A
SCHEMBL12169057 0.94 CYP17A1 (0.41) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL17366404 0.94 KDM4E (0.38) MAPK10KDM4EATML3MBTL1KMT2A
SCHEMBL12169056 0.94 KDM4E (0.38) MAPK10KDM4EATML3MBTL1KMT2A
SCHEMBL12169082 0.94 CYP11B2 (0.42) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL12442771 0.93 CYP17A1 (0.43) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL12098142 0.93 CYP17A1 (0.42) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL12169020 0.93 CYP17A1 (0.42) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10
SCHEMBL12169016 0.93 CYP17A1 (0.42) CYP11B1CYP11B2CYP19A1CYP17A1MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3255692-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-07-05 EP disclosed
EP-3282496-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-04-26 EP disclosed
EP-3244465-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2022-04-20 EP disclosed
US-11158811-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-10892420-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2021-01-12 US disclosed
US-10818844-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-10-27 US disclosed
US-10693078-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-06-23 US disclosed
US-10593884-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-10566540-B2 Organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2020-02-18 US disclosed
US-10505119-B2 Organic electroluminescence device HODOGAYA CHEMICAL CO., LTD. (JP) 2019-12-10 US disclosed
US-20170117481-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
WO-2016163276-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-10-13 WO disclosed
WO-2016125706-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-08-11 WO disclosed
WO-2016111254-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-07-14 WO disclosed
WO-2016079944-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-05-26 WO disclosed
WO-2016013184-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2016-01-28 WO disclosed
US-20150380657-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2015-12-31 US disclosed
US-20150380657-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2015-12-31 US disclosed
EP-2960958-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2015-12-30 EP disclosed
WO-2015198563-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2015-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593884-B2 Organic electroluminescent device AHR, SLC18A1, KCNH1 CYP11B1 272/4885CYP11B2 470/4885CYP19A1 42/4885
US-10693078-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNH3 CYP11B1 2460/4885CYP11B2 1737/4885CYP19A1 638/4885
US-10505119-B2 Organic electroluminescence device AHR, ARNT, NAT1 CYP11B1 563/4885CYP11B2 827/4885CYP19A1 354/4885
US-20170117481-A1 ORGANIC ELECTROLUMINESCENT DEVICE KCNN2, KCNN1, SLC7A5 CYP11B1 1550/4885CYP11B2 1078/4885CYP19A1 224/4885
US-10818844-B2 Organic electroluminescent device AHR, ARNT, TRPV4 CYP11B1 480/4885CYP11B2 624/4885CYP19A1 365/4885
US-10566540-B2 Organic electroluminescent device KCNN2, SLC7A5, KCNN1 CYP11B1 1702/4885CYP11B2 1330/4885CYP19A1 527/4885
US-10892420-B2 Organic electroluminescent device SLC7A5, KCNN2, SLC43A1 CYP11B1 2072/4885CYP11B2 1737/4885CYP19A1 626/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.