SCHEMBL17387207

SCHEMBL17387207

Cc1c(F)cc(F)cc1[B-](c1cc(F)cc(F)c1C)(c1cc(F)cc(F)c1C)c1cc(F)cc(F)c1C.[H+]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.33
HDAC4 P56524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4376449 0.98 RAPGEF4 (0.34) RAPGEF4HDAC4
SCHEMBL5083906 0.80 NPC1 (0.30)
SCHEMBL6065224 0.76
SCHEMBL67360 0.76 RAPGEF4 (0.42) RAPGEF4HDAC4
SCHEMBL6064837 0.75 TRPM8 (0.32)
SCHEMBL6064835 0.74 TAAR1 (0.34)
SCHEMBL6065757 0.73 PKM (0.35)
SCHEMBL6065494 0.73 HDAC4 (0.35) HDAC4
SCHEMBL6065751 0.73
SCHEMBL6065761 0.73 TRPM8 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORPORATION (JP) 2018-06-26 US disclosed
EP-3078670-B1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORP (JP) 2017-12-27 EP disclosed
US-20170320981-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2017-11-09 US disclosed
US-9783625-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORPORATION (JP) 2017-10-10 US disclosed
EP-2963045-B1 METHOD FOR PRODUCING OLEFIN POLYMER WITH A METALLOCENE BASED CATALYST, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORP (JP) 2016-12-21 EP disclosed
EP-3078670-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2016-10-12 EP disclosed
US-20160009838-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER JAPAN POLYETHYLENE CORPORATION (JP) 2016-01-14 US disclosed
EP-2963045-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER Japan Polyethylene Corporation (JP) 2016-01-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170320981-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER CPNE4, PIN4, PIN1 RAPGEF4 904/4885HDAC4 1971/4885
US-20160009838-A1 METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER CPNE4, ALOX12, PIN1 RAPGEF4 1405/4885HDAC4 2680/4885
US-10005864-B2 Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer CPNE4, PPOX, PIN1 RAPGEF4 690/4885HDAC4 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.