Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 13/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | PNLIP | P16233 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 3/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186292 | 0.81 | SOD1 (0.43) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Salvinolone SCHEMBL29931087 | 0.79 | FDPS (0.45) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL16006738 | 0.77 | FDPS (0.36) | FDPSGGPS1MEN1KMT2AALDH1A1 | |
| SCHEMBL4778751 | 0.74 | CACNA1G (0.31) | — | |
| SCHEMBL18290374 | 0.70 | FDPS (0.49) | FDPSGGPS1PTGESPNLIPMEN1 | |
| SCHEMBL18290301 | 0.68 | SOD1 (0.47) | FDPSGGPS1CYP3A4MAPTCYP2C9 | |
| SCHEMBL18290239 | 0.68 | SOD1 (0.47) | FDPSGGPS1CYP3A4MAPTCYP2C9 | |
| SCHEMBL30190097 | 0.68 | HIF1A (0.37) | — | |
| Demethylcryptojaponol SCHEMBL16006713 | 0.66 | FDPS (0.67) | FDPSGGPS1PTGESPNLIPMEN1 | |
| Demethylcryptojaponol SCHEMBL13532270 | 0.66 | FDPS (0.67) | FDPSGGPS1PTGESPNLIPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2022067052-A | COMPOSITION OF PLECTRANTHUS BARBATUS EXTRACT FREE OF 14-DEOXYCOLEON U AND SYNTHESIS METHOD | スター ハイ ハーブス ピーヴィーティー エルティーディー． | 2022-05-02 | — | — | JP | disclosed |
| JP-2022067052-A | COMPOSITION OF PLECTRANTHUS BARBATUS EXTRACT FREE OF 14-DEOXYCOLEON U AND SYNTHESIS METHOD | スター ハイ ハーブス ピーヴィーティー エルティーディー． | 2022-05-02 | — | — | JP | disclosed |
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | MMP8, GUSB, MMP9 | FDPS 995/4885GGPS1 749/4885PTGES 250/4885 |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | FDPS 995/4885GGPS1 749/4885PTGES 250/4885 |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | FDPS 995/4885GGPS1 749/4885PTGES 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.