Salvinolone

Salvinolone

SCHEMBL29931087

CC(C)c1cc2c(c(O)c1O)[C@@]1(C)CCCC(C)(C)C1=CC2=O

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FDPS P14324 13/20 0.45
▸ GGPS1 O95749 6/20 0.45
▸ CACNA1G O43497 1/20 0.44
▸ PTGES O14684 2/20 0.42
▸ PNLIP P16233 2/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ BCL9 O00512 3/20 0.41
▸ CTNNB1 P35222 3/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ CYP3A4 P08684 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HPGD P15428 2/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ ALOX12 P18054 1/20 0.41
▸ GSTO1 P78417 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.41
▸ USP2 O75604 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17403057 0.80 CACNA1G (0.44) FDPSGGPS1CACNA1GPTGESPNLIP
14-Deoxycoleon U SCHEMBL17403056 0.79 FDPS (0.43) FDPSGGPS1PTGESPNLIPMEN1
SCHEMBL17403058 0.73 CACNA1G (0.42) FDPSGGPS1CACNA1GMEN1KMT2A
SCHEMBL18290213 0.68 SOD1 (0.41) FDPSGGPS1CACNA1GPTGESPNLIP
Demethylcryptojaponol SCHEMBL16006713 0.68 FDPS (0.67) FDPSGGPS1PTGESPNLIPMEN1
Demethylcryptojaponol SCHEMBL28596866 0.68 FDPS (0.67) FDPSGGPS1PTGESPNLIPMEN1
Demethylcryptojaponol SCHEMBL13532270 0.68 FDPS (0.67) FDPSGGPS1PTGESPNLIPMEN1
SCHEMBL18290374 0.67 FDPS (0.49) FDPSGGPS1PTGESPNLIPMEN1
6-Alpha-Hydroxydemethyl-Cryptojaponol SCHEMBL18290237 0.66 SOD1 (0.54) FDPSGGPS1PTGESPNLIPMEN1
SCHEMBL3186292 0.65 SOD1 (0.43) FDPSGGPS1PTGESPNLIPMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118771970-A Accurate separation method and application of Salvinolone serving as natural free radical scavenger in Salvia root of Salvia 青海大学 2024-10-15 — — CN claimed
CN-118771970-A Accurate separation method and application of Salvinolone serving as natural free radical scavenger in Salvia root of Salvia 青海大学 2024-10-15 — — CN disclosed
CN-118771970-A Accurate separation method and application of Salvinolone serving as natural free radical scavenger in Salvia root of Salvia 青海大学 2024-10-15 — — CN disclosed
CN-118771970-A Accurate separation method and application of Salvinolone serving as natural free radical scavenger in Salvia root of Salvia 青海大学 2024-10-15 — — CN disclosed
US-20230027219-A1 Skin Care Compositions and Methods of Use Thereof UNIGEN, INC. (US) 2023-01-26 — — US disclosed
US-11446225-B2 Skin care compositions and methods of use thereof UNIGEN, INC. (US) 2022-09-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027219-A1 Skin Care Compositions and Methods of Use Thereof CUTA, LGALS8, RBP1 FDPS 4632/4885GGPS1 4717/4885CACNA1G 3723/4885
US-11446225-B2 Skin care compositions and methods of use thereof CUTA, LGALS8, RBP1 FDPS 4632/4885GGPS1 4717/4885CACNA1G 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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