Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOD1 | P00441 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 5/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16006738 | 0.86 | FDPS (0.36) | SOD1FDPSGGPS1IDO1MAPT | |
| SCHEMBL18290301 | 0.86 | SOD1 (0.47) | SOD1KARS1FDPSGGPS1IDO1 | |
| SCHEMBL18290239 | 0.86 | SOD1 (0.47) | SOD1KARS1FDPSGGPS1IDO1 | |
| SCHEMBL18290356 | 0.81 | SOD1 (0.38) | SOD1KARS1IDO1HIF1ACYP1A2 | |
| 14-Deoxycoleon U SCHEMBL17403056 | 0.81 | FDPS (0.43) | SOD1FDPSGGPS1CYP3A4TP53 | |
| SCHEMBL19915508 | 0.81 | SOD1 (0.42) | SOD1KARS1FDPSGGPS1HIF1A | |
| SCHEMBL17403057 | 0.78 | CACNA1G (0.44) | SOD1KARS1FDPSGGPS1HIF1A | |
| SCHEMBL18290304 | 0.70 | KARS1 (0.42) | SOD1KARS1HIF1ACYP1A2CYP2D6 | |
| SCHEMBL18290213 | 0.70 | SOD1 (0.41) | SOD1KARS1FDPSGGPS1HIF1A | |
| Hypargenin C SCHEMBL18290364 | 0.69 | SOD1 (0.55) | SOD1KARS1FDPSGGPS1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2018-03-01 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| US-9809615-B2 | Anti-cancer compounds from invasive salvinias and methods of treating cancer | STEPHEN F. AUSTIN STATE UNIVERSITY (US) | 2017-11-07 | — | — | US | disclosed |
| WO-2016192631-A1 | ABIETANE-TYPE DITERPENE COMPOUND HAVING LIPID-LOWERING ACTIVITY, METHOD FOR PREPARING SAME, AND USE OF SAME | 中国科学院上海药物研究所 | 2016-12-08 | — | — | WO | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | STEPHEN F. AUSTIN STATE UNIVERSITY | 2016-01-07 | — | — | US | disclosed |
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |
| US-8519007-B2 | Use certain diterpene compounds in the treatment of androgen receptor-associated diseases | ACADEMIA SINICA (TW) | 2013-08-27 | — | — | US | disclosed |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | ACADEMIA SINICA (TW) | 2010-01-28 | — | — | US | disclosed |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | ACADEMIA SINICA (TW) | 2010-01-28 | — | — | US | disclosed |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | ACADEMIA SINICA (TW) | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10464963-B2 | Compounds from invasive Salvinias and methods of using the same | MMP8, GUSB, MMP9 | SOD1 2517/4885KARS1 2969/4885FDPS 995/4885 |
| US-20180057524-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | SOD1 2517/4885KARS1 2969/4885FDPS 995/4885 |
| US-20100022632-A1 | USE CERTAIN DITERPENE COMPOUNDS IN THE TREATMENT OF ANDROGEN RECEPTOR-ASSOCIATED DISEASES | AR, CYP17A1, CYP19A1 | SOD1 4841/4885KARS1 3258/4885FDPS 178/4885 |
| US-20160002279-A1 | COMPOUNDS FROM INVASIVE SALVINIAS AND METHODS OF USING THE SAME | MMP8, GUSB, MMP9 | SOD1 2517/4885KARS1 2969/4885FDPS 995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.