Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332174 | 0.78 | KMT2A (0.67) | KMT2ALMNASMN1; SMN2KDM4ERCE1 | |
| SCHEMBL14463630 | 0.73 | PTGS2 (0.58) | AGTR1KMT2APADI4LMNASMN1; SMN2 | |
| SCHEMBL17423697 | 0.71 | EGFR (0.47) | AGTR1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL14288833 | 0.71 | ALDH1A1 (0.66) | KMT2APADI4LMNASMN1; SMN2KDM4E | |
| SCHEMBL5335958 | 0.69 | TACR1 (0.58) | AGTR1KMT2APADI4LMNAKDM4E | |
| SCHEMBL2490336 | 0.68 | AGTR1 (0.53) | AGTR1KMT2ALMNASMN1; SMN2KDM4E | |
| SCHEMBL29655556 | 0.68 | KMT2A (0.40) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL5189056 | 0.68 | KMT2A (0.40) | KMT2ALMNAKDM4EALDH1A1POLB | |
| SCHEMBL29262209 | 0.68 | LMNA (0.55) | AGTR1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5339664 | 0.68 | TACR1 (0.59) | AGTR1KMT2APADI4LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248934-A | Heteroaryl PAD4 inhibitor | 帕德罗科治疗公司 | 2019-09-17 | — | — | CN | disclosed |