SCHEMBL17425632

SCHEMBL17425632

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc4c3oc3c(-c5ccccc5)cccc34)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
TSHR P16473 4/20 0.46
KDM4E B2RXH2 4/20 0.46
MAPT P10636 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
TP53 P04637 2/20 0.46
NFKB1 P19838 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ATM Q13315 2/20 0.46
HPGD P15428 1/20 0.46
MAPK1 P28482 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PRKDC P78527 5/20 0.45
PIK3CD O00329 3/20 0.45
PIK3CA P42336 3/20 0.45
PIK3CB P42338 3/20 0.45
PIK3CG P48736 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20871989 1.00 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL30103566 1.00 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL18216709 0.98 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL16441438 0.98 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL21343772 0.98 MAPT (0.47) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL24216935 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL21563813 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL17425705 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL24217269 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT
SCHEMBL24525894 0.97 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TSHRKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-09-21 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 US disclosed
EP-4167707-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-04-19 EP disclosed
EP-3591728-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-12-14 EP disclosed
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed
US-20190280216-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY AND LIGHTING DEVICE MERCK PATENT GMBH (DE) 2019-09-12 US disclosed
EP-2966706-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2019-09-04 EP disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 US disclosed
WO-2019142555-A1 LUMINESCENT FILM, ORGANIC ELECTROLUMINESCENT DEVICE, AND METHOD FOR MANUFACTURING ORGANIC ELECTROLUMINESCENT DEVICE コニカミノルタ株式会社 2019-07-25 WO disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 US disclosed
US-20170054087-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-02-23 US disclosed
US-20160093808-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-03-31 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-01-28 US disclosed
EP-2966706-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2016-01-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028021-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 ALDH1A1 1130/4885SMN1; SMN2 2722/4885TSHR 4306/4885
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM ALDH1A1 606/4885SMN1; SMN2 1453/4885TSHR 4514/4885
US-20220213116-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF PIEZO1, LEF1, TMEM109 ALDH1A1 129/4885SMN1; SMN2 2171/4885TSHR 4817/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM ALDH1A1 606/4885SMN1; SMN2 1453/4885TSHR 4514/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 ALDH1A1 1130/4885SMN1; SMN2 2722/4885TSHR 4306/4885
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 ALDH1A1 14/4885SMN1; SMN2 4327/4885TSHR 4694/4885
US-20230301183-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 ALDH1A1 7/4885SMN1; SMN2 4365/4885TSHR 4296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.