Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6828432 | 0.80 | CA2 (0.39) | LMNA | |
| SCHEMBL27449562 | 0.71 | — | — | |
| SCHEMBL384644 | 0.70 | TRPV4 (0.38) | TRPV4LMNAMEN1KMT2A | |
| SCHEMBL5559189 | 0.70 | LMNA (0.33) | TRPV4LMNAMEN1KMT2A | |
| SCHEMBL2802756 | 0.68 | HTR6 (0.45) | TRPV4LMNAMEN1KMT2A | |
| SCHEMBL11484963 | 0.68 | LMNA (0.36) | TRPV4LMNAMEN1KMT2A | |
| SCHEMBL1035114 | 0.68 | LMNA (0.32) | LMNAMEN1KMT2A | |
| SCHEMBL8735595 | 0.68 | — | — | |
| SCHEMBL16799844 | 0.67 | CASP3 (0.36) | — | |
| SCHEMBL15352797 | 0.64 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387559-A1 | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | Abbott Laboratories (US) | 2011-11-23 | — | — | EP | disclosed |