SCHEMBL1743186

SCHEMBL1743186

N=C(N)Nc1ccc(Cc2ccc(NC(=N)N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 4/20 0.50
ADRA2B P18089 4/20 0.50
ADRA2C P18825 4/20 0.50
POLB P06746 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
SAE1 Q9UBE0 3/20 0.43
UBA2 Q9UBT2 3/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 2/20 0.42
LTA4H P09960 1/20 0.41
SLC1A3 P43003 1/20 0.41
SLC1A2 P43004 1/20 0.41
SLC1A1 P43005 1/20 0.41
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
TMPRSS6 Q8IU80 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3775513 0.92 SLC1A3 (0.51) ADRA2AADRA2BADRA2CPOLBLMNA
SCHEMBL27589604 0.89 TSHR (0.60) POLBKMT2AMEN1LMNATSHR
Hydrochloric Acid SCHEMBL6158030 0.87 TSHR (0.58) POLBKMT2AMEN1LMNATSHR
SCHEMBL3785285 0.86 AOC3 (0.45) F2PRSS1PRSS2PRSS3TMPRSS6
SCHEMBL1996992 0.85 F2 (0.50) TSHRALDH1A1F2PRSS1PRSS2
SCHEMBL20553484 0.84 PRSS1 (0.54) ADRA2AADRA2BADRA2CKMT2AMEN1
SCHEMBL327252 0.84 LOXL2 (0.54) PRSS1ST14
SCHEMBL13976972 0.84 NOS1 (0.49) ADRA2AADRA2BADRA2CPOLBKMT2A
Hydrochloric Acid SCHEMBL7443406 0.83 LOXL2 (0.52) PRSS1
Hydrochloric Acid SCHEMBL6157588 0.83 PRSS1 (0.52) ADRA2AADRA2BADRA2CKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2025-11-25 US disclosed
EP-4174053-B1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO LTD (JP) 2025-11-19 EP disclosed
EP-4569023-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2025-06-18 EP disclosed
WO-2024033348-A1 COMBINATION OF CATALYTIC COMPONENTS POLYU GMBH (DE) 2024-02-15 WO disclosed
EP-4321573-A1 COMBINATION OF CATALYTIC COMPONENTS PolyU GmbH (DE) 2024-02-14 EP disclosed
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT NITTO KASEI CO., LTD. (JP) 2023-07-27 US disclosed
EP-4180482-A1 MOISTURE-CURABLE COMPOSITION Nitto Kasei Co., Ltd. (JP) 2023-05-17 EP disclosed
EP-4174053-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT Nitto Kasei Co., Ltd. (JP) 2023-05-03 EP disclosed
EP-2837660-B1 CURABLE COMPOSITION, AND CURED SYNTHETIC RESIN USING SAME UNIV MIE (JP) 2021-07-14 EP disclosed
EP-2837660-A1 CURABLE COMPOSITION, AND CURED SYNTHETIC RESIN USING SAME Mie University (JP) 2015-02-18 EP disclosed
US-8853309-B2 Curable composition and cured product thereof KANEKA CORPORATION (JP) 2014-10-07 US disclosed
EP-2338938-B1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORP (JP) 2013-07-31 EP disclosed
EP-2388297-A1 CURABLE COMPOSITION AND CURED OBJECT FORMED THEREFROM Kaneka Corporation (JP) 2011-11-23 EP disclosed
US-20110237723-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF KANEKA CORPORATION (JP) 2011-09-29 US disclosed
EP-2338938-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Kaneka Corporation (JP) 2011-06-29 EP disclosed
US-20100331384-A1 GUANIDINE BASED COMPOUNDS UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) 2010-12-30 US disclosed
US-20100331384-A1 GUANIDINE BASED COMPOUNDS UNIVERSIDAD DEL PAIS VASCO/EUSKAL HERRIKO UNIBERTSITATEA (ES) 2010-12-30 US disclosed
EP-2267083-A1 CURABLE COMPOSITION AND CURED MATERIAL Kaneka Corporation (JP) 2010-12-29 EP disclosed
WO-2009080818-A2 GUANIDINE BASED COMPOUNDS THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2009-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479869-B2 Curing catalyst used for curing of polymer, method for producing same, moisture-curable composition, and method for producing cured product KDM2B, SETDB1, ASH2L ADRA2A 3479/4885ADRA2B 1673/4885ADRA2C 4216/4885
US-20230234976-A1 CURING CATALYST USED FOR CURING OF POLYMER, METHOD FOR PRODUCING SAME, MOISTURE-CURABLE COMPOSITION, AND METHOD FOR PRODUCING CURED PRODUCT KDM2B, SETDB1, ASH2L ADRA2A 3479/4885ADRA2B 1673/4885ADRA2C 4216/4885
US-20100331384-A1 GUANIDINE BASED COMPOUNDS ADRB2, ADRA2A, ADRA2C ADRA2A 2/4885ADRA2B 6/4885ADRA2C 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.