SCHEMBL1743872

SCHEMBL1743872

Clc1nccc2c1sc1ccc(Br)cc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPM2A O95278 1/20 0.35
PTPN2 P17706 1/20 0.35
PTPN1 P18031 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.35
PIM1 P11309 2/20 0.35
PIM2 Q9P1W9 2/20 0.35
CYP2A6 P11509 2/20 0.35
HRH4 Q9H3N8 3/20 0.34
CHUK O15111 1/20 0.34
IDO1 P14902 1/20 0.34
MIF P14174 1/20 0.33
EGFR P00533 2/20 0.32
PLG P00747 1/20 0.32
PLAU P00749 1/20 0.32
PLAT P00750 1/20 0.32
HSP90AA1 P07900 1/20 0.32
HTT P42858 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25464256 0.81 ROCK1 (0.36) PIM1PIM2CYP2A6IDO1ROCK1
SCHEMBL22698574 0.77 EPM2A (0.35) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL30450607 0.77 EPM2A (0.35) EPM2APTPN2PTPN1PTPN22CYP2A6
SCHEMBL10227293 0.77 EPM2A (0.44) EPM2APTPN2PTPN1PTPN22PIM1
SCHEMBL442331 0.76 GPR3 (0.46) ROCK1
SCHEMBL30967228 0.76 GPR3 (0.46) ROCK1
SCHEMBL20137415 0.74 MAPT (0.44) CYP2A6PLAU
SCHEMBL15989756 0.73 IDO1 (0.38) EPM2APTPN2PTPN1PTPN22PIM1
SCHEMBL30577776 0.73 IDO1 (0.38) EPM2APTPN2PTPN1PTPN22PIM1
SCHEMBL25171509 0.73 BCKDK (0.39) HRH4HTTGAAROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956268-B 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method 西安欧得光电材料有限公司 2022-07-15 CN claimed
CN-113956268-A 6-bromo-1-chlorobenzothiophene [2,3-c ] pyridine and synthetic method 西安欧得光电材料有限公司 2022-01-21 CN claimed
CN-116640152-A Benzothiophene pyridine derivative and synthesis method thereof 西安欧得光电材料有限公司 2023-08-25 CN disclosed
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-07-06 US disclosed
US-20230157152-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
US-20230157152-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157152-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-05-18 US disclosed
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed
CN-116120375-A Organometallic compound, light-emitting device including the same, and electronic apparatus including the light-emitting device 三星电子株式会社 2023-05-16 CN disclosed
US-20150274749-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-01 US disclosed
US-9067947-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-30 US disclosed
WO-2015063046-A1 AZADIBENZOTHIOPHENES FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2015-05-07 WO disclosed
US-8952363-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-02-10 US disclosed
EP-2703405-A2 New materials with aza-dibenzothiophene or aza-dibenzofuran core for pholed Universal Display Corporation (US) 2014-03-05 EP disclosed
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2013-03-07 US disclosed
EP-2387576-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED Universal Display Corporation (US) 2011-11-23 EP disclosed
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-29 US disclosed
WO-2010083359-A2 NEW MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED UNIVERSAL DISPLAY CORPORATION (US) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150274749-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES DDT, AZI2, EED EPM2A 787/4885PTPN2 1718/4885PTPN1 2610/4885
US-20230157152-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CYBA, INTS9, CNOT9 EPM2A 1923/4885PTPN2 2162/4885PTPN1 2302/4885
US-20230217823-A1 ORGANIC ELECTROLUMINESCENT DEVICE LEF1, EPB41L2, CTNNBL1 EPM2A 340/4885PTPN2 3851/4885PTPN1 3540/4885
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, EHD1 EPM2A 2022/4885PTPN2 3300/4885PTPN1 1901/4885
US-20130060037-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 EPM2A 2651/4885PTPN2 324/4885PTPN1 463/4885
US-20100187984-A1 MATERIALS WITH AZA-DIBENZOTHIOPHENE OR AZA-DIBENZOFURAN CORE FOR PHOLED DDT, FZD7, BRD7 EPM2A 2651/4885PTPN2 324/4885PTPN1 463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.