Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468913 | 0.81 | CYP19A1 (0.38) | ALDH1A1MAPT | |
| SCHEMBL17469136 | 0.78 | SLC6A2 (0.32) | — | |
| SCHEMBL17469009 | 0.77 | ABHD6 (0.34) | ALDH1A1LMNAMAPT | |
| SCHEMBL17469002 | 0.77 | ABHD6 (0.36) | ALDH1A1MAPT | |
| SCHEMBL17459385 | 0.77 | TAS1R3 (0.38) | — | |
| SCHEMBL17468800 | 0.77 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL17468801 | 0.77 | POLB (0.36) | ALDH1A1MAPT | |
| SCHEMBL17468799 | 0.76 | ALDH1A1 (0.40) | ALDH1A1NPSR1 | |
| SCHEMBL17468798 | 0.76 | TAS1R3 (0.38) | ALDH1A1 | |
| SCHEMBL17469012 | 0.75 | NAMPT (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |