Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17468798 | 0.90 | TAS1R3 (0.38) | ABHD6NAMPTALDH1A1AHRHPGD | |
| SCHEMBL17468801 | 0.88 | POLB (0.36) | ABHD6ALDH1A1MAPTALOX15AHR | |
| SCHEMBL17469009 | 0.87 | ABHD6 (0.34) | ABHD6TSHRALDH1A1MAPTHTR6 | |
| SCHEMBL17468913 | 0.84 | CYP19A1 (0.38) | ABHD6TSHRALDH1A1MAPK1KDM4E | |
| SCHEMBL17468800 | 0.82 | ALDH1A1 (0.35) | ABHD6NAMPTALDH1A1HPGDNPC1 | |
| SCHEMBL17459385 | 0.80 | TAS1R3 (0.38) | NAMPTGAALTA4H | |
| SCHEMBL17469012 | 0.80 | NAMPT (0.41) | ABHD6NAMPTSIRT2SIRT1 | |
| SCHEMBL17469136 | 0.79 | SLC6A2 (0.32) | NPC1RAB9A | |
| SCHEMBL17468797 | 0.78 | LTA4H (0.33) | ABHD6NAMPTALDH1A1MAPK1MAPT | |
| SCHEMBL17469007 | 0.77 | AR (0.38) | MAPTHTR6RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |