Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746183 | 0.92 | TRPA1 (0.44) | MAPTSMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL2462990 | 0.80 | TMEM97 (0.43) | MAPTSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL8977956 | 0.73 | ALDH1A1 (0.43) | MAPTSMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL5093206 | 0.73 | LOXL2 (0.50) | MAPTSMN1; SMN2KMT2ANR3C1PGR | |
| SCHEMBL3461796 | 0.73 | MAPT (0.49) | MAPTSMN1; SMN2 | |
| SCHEMBL2832480 | 0.72 | APP (0.66) | MAPTSMN1; SMN2PTGS2NPC1RAB9A | |
| SCHEMBL23146337 | 0.72 | TMEM97 (0.45) | MAPTSMN1; SMN2MEN1KMT2ATRPA1 | |
| SCHEMBL1747643 | 0.72 | TMEM97 (0.42) | MAPTSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL23146060 | 0.72 | SIGMAR1 (0.42) | MAPTSMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL1081575 | 0.72 | TMEM97 (0.45) | MAPTSMN1; SMN2MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2104547-A | — | — | None | — | — | JP | disclosed |
| EP-0350113-B1 | Liquid crystalline polyesters | AKZO NOBEL NV (NL) | 1995-01-25 | — | — | EP | disclosed |
| EP-0350112-B1 | POLYURETHANES PREPARED FROM NON-LINEAR OPTICAL ACTIVE DIOLS | Akzo Nobel N.V. (NL) | 1993-10-06 | — | — | EP | disclosed |
| US-5001209-A | Non-linear optical active diols and polyurethanes prepared therefrom | AKZO N.V. (NL) | 1991-03-19 | — | — | US | disclosed |
| US-4959448-A | Optical waveguides | AKZO N.V. (NL) | 1990-09-25 | — | — | US | disclosed |
| JP-H02104547-A | NON-LINEAR OPTICALLY ACTIVE DIOL AND POLYURETHANE PREPARED THEREFROM | AKZO NV | 1990-04-17 | — | — | JP | disclosed |
| EP-0350112-A1 | Polyurethanes prepared from non-linear optical active diols | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |
| EP-0350113-A1 | Liquid crystalline polyesters | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |