Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469291 | 0.82 | KMT2A (0.56) | MEN1KMT2AL3MBTL1ALDH1A1IDO1 | |
| SCHEMBL17469290 | 0.81 | KMT2A (0.42) | MEN1KMT2AL3MBTL1KDM4EATM | |
| SCHEMBL17469277 | 0.81 | KMT2A (0.40) | MEN1KMT2AL3MBTL1ATMALDH1A1 | |
| SCHEMBL17469283 | 0.80 | MEN1 (0.39) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469287 | 0.80 | KMT2A (0.39) | MEN1KMT2AL3MBTL1ATMALDH1A1 | |
| SCHEMBL17469272 | 0.75 | MAPT (0.45) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19322245 | 0.74 | KDM4E (0.40) | MEN1KMT2ABACE1KDM4EATM | |
| SCHEMBL24236617 | 0.71 | TSHR (0.45) | KDM4EALDH1A1MAPT | |
| SCHEMBL24236616 | 0.66 | PLA2G2A (0.58) | MEN1KMT2AALDH1A1 | |
| SCHEMBL28032229 | 0.66 | TUBB4A (0.41) | MEN1KMT2AKDM4EALDH1A1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |