Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | MST1R | Q04912 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469290 | 0.87 | KMT2A (0.42) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469291 | 0.86 | KMT2A (0.56) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469287 | 0.86 | KMT2A (0.39) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469283 | 0.86 | MEN1 (0.39) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469288 | 0.81 | MEN1 (0.40) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL24236617 | 0.79 | TSHR (0.45) | ALDH1A1TSHRMTNR1AMTNR1B | |
| SCHEMBL17469272 | 0.78 | MAPT (0.45) | KMT2AMEN1L3MBTL1ALDH1A1HTT | |
| SCHEMBL19322243 | 0.70 | NCOA1 (0.41) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469273 | 0.67 | POLB (0.46) | ALDH1A1LMNATSHRIDO1HTT | |
| SCHEMBL17469278 | 0.67 | KDM4E (0.44) | KMT2AMEN1ALDH1A1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |