Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469277 | 0.86 | KMT2A (0.40) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469290 | 0.86 | KMT2A (0.42) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469283 | 0.85 | MEN1 (0.39) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469287 | 0.85 | KMT2A (0.39) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469288 | 0.82 | MEN1 (0.40) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469272 | 0.77 | MAPT (0.45) | KMT2AMEN1L3MBTL1ALDH1A1HTT | |
| SCHEMBL14158941 | 0.72 | KMT2A (1.00) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL19322239 | 0.71 | L3MBTL1 (0.51) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL29051469 | 0.69 | HTT (0.51) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL24236643 | 0.69 | MEN1 (0.49) | KMT2AMEN1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |