Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469290 | 0.86 | KMT2A (0.42) | MEN1KMT2AL3MBTL1RORCALDH1A1 | |
| SCHEMBL17469277 | 0.86 | KMT2A (0.40) | MEN1KMT2AL3MBTL1RORCALDH1A1 | |
| SCHEMBL17469287 | 0.85 | KMT2A (0.39) | MEN1KMT2AL3MBTL1RORCALDH1A1 | |
| SCHEMBL17469291 | 0.85 | KMT2A (0.56) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469288 | 0.80 | MEN1 (0.40) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469272 | 0.77 | MAPT (0.45) | MEN1KMT2AL3MBTL1ALDH1A1NPSR1 | |
| SCHEMBL19322240 | 0.71 | MTNR1A (0.42) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL24236617 | 0.69 | TSHR (0.45) | ALDH1A1TSHRMTNR1AMTNR1BPLA2G2A | |
| SCHEMBL17469273 | 0.66 | POLB (0.46) | ALDH1A1LMNATSHRNPSR1MTNR1A | |
| SCHEMBL17469278 | 0.66 | KDM4E (0.44) | MEN1KMT2AALDH1A1LMNAMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |