Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469277 | 0.87 | KMT2A (0.40) | KMT2AMEN1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17469283 | 0.86 | MEN1 (0.39) | KMT2AMEN1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17469291 | 0.86 | KMT2A (0.56) | KMT2AMEN1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17469287 | 0.86 | KMT2A (0.39) | KMT2AMEN1L3MBTL1ALDH1A1TSHR | |
| SCHEMBL17469288 | 0.81 | MEN1 (0.40) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL17469272 | 0.78 | MAPT (0.45) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19322244 | 0.70 | PDE3B (0.39) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL24236617 | 0.67 | TSHR (0.45) | ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL17469273 | 0.67 | POLB (0.46) | ALDH1A1TSHRLMNAMAPTIDO1 | |
| SCHEMBL17469278 | 0.67 | KDM4E (0.44) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |