Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469273 | 0.82 | POLB (0.46) | KDM4EPOLBSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL17469272 | 0.82 | MAPT (0.45) | KDM4EPOLBSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL19317475 | 0.73 | AGER (0.41) | KDM4EPOLBPKMAGERSMN1; SMN2 | |
| SCHEMBL28062874 | 0.70 | ALOX5 (0.43) | KDM4EPOLBHSD17B10GAAHTT | |
| SCHEMBL17469290 | 0.67 | KMT2A (0.42) | KDM4EALDH1A1LMNAHTTMAPT | |
| SCHEMBL17469277 | 0.67 | KMT2A (0.40) | ALDH1A1MTNR1ALMNAHTTMEN1 | |
| SCHEMBL24653904 | 0.67 | KAT6A (0.50) | KDM4EALDH1A1GAANPC1RAB9A | |
| SCHEMBL1489103 | 0.67 | AGER (0.52) | KDM4EPOLBPKMAGERSMN1; SMN2 | |
| SCHEMBL17469291 | 0.66 | KMT2A (0.56) | POLBSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL17469287 | 0.66 | KMT2A (0.39) | ALDH1A1MTNR1ALMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028060-A1 | NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |