Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469278 | 0.82 | KDM4E (0.44) | POLBMAPTSMN1; SMN2HSD17B10MTNR1A | |
| SCHEMBL17469272 | 0.82 | MAPT (0.45) | POLBMAPTNPSR1SMN1; SMN2HSD17B10 | |
| SCHEMBL19317473 | 0.73 | MTNR1A (0.38) | POLBMAPTNPSR1PPARGMTNR1A | |
| SCHEMBL28062874 | 0.70 | ALOX5 (0.43) | POLBHSD17B10HTTKDM4EGAA | |
| SCHEMBL17469290 | 0.67 | KMT2A (0.42) | MAPTHTTALDH1A1KDM4ETSHR | |
| SCHEMBL17469277 | 0.67 | KMT2A (0.40) | MTNR1AHTTALDH1A1TSHRLMNA | |
| SCHEMBL17469291 | 0.66 | KMT2A (0.56) | POLBMAPTSMN1; SMN2HTTALDH1A1 | |
| SCHEMBL17469287 | 0.66 | KMT2A (0.39) | MTNR1AHTTALDH1A1TSHRLMNA | |
| SCHEMBL24236616 | 0.66 | PLA2G2A (0.58) | POLBALDH1A1TSHR | |
| SCHEMBL17469288 | 0.64 | MEN1 (0.40) | MAPTSMN1; SMN2HTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020028060-A1 | NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2020-02-06 | — | — | WO | disclosed |
| WO-2016014426-A1 | ORGANIC REACTIONS | THE ARIZONA BOARD OF REGENTS (US) | 2016-01-28 | — | — | WO | disclosed |