Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17471132 | 0.84 | NAMPT (0.43) | LMNAHTTCYP2D6KCNH2HRH3 | |
| SCHEMBL18557408 | 0.83 | ALDH1A1 (0.46) | LMNAHTTP2RX4TDP1DNM1 | |
| SCHEMBL17471820 | 0.81 | CYP2C19 (0.50) | LMNAHTTCYP2D6KCNH2HRH3 | |
| SCHEMBL13225898 | 0.78 | KMT2A (0.62) | LMNAHTTCYP2D6KCNH2HRH3 | |
| SCHEMBL17471147 | 0.77 | LMNA (0.52) | LMNAHTTCYP2D6ALDH1A1 | |
| SCHEMBL19698170 | 0.76 | TPSAB1 (0.37) | LMNAHTTCYP2D6KCNH2HRH3 | |
| SCHEMBL17471129 | 0.75 | HDAC2 (0.42) | HTTCYP2D6KCNH2HRH3EPHX2 | |
| SCHEMBL17471127 | 0.75 | TPSAB1 (0.45) | CYP2D6KCNH2HRH3NAMPTTPSAB1 | |
| SCHEMBL19698171 | 0.75 | DRD2 (0.39) | LMNAHTTALDH1A1NAMPTTPSAB1 | |
| SCHEMBL19698161 | 0.74 | MGLL (0.41) | LMNAHTTALDH1A1NAMPTTPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9580415-B2 | Compounds | PROXIMAGEN LIMITED (GB) | 2017-02-28 | — | — | US | disclosed |
| US-20160024080-A1 | NEW COMPOUNDS | PROXIMAGEN, LLC | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024080-A1 | NEW COMPOUNDS | QSOX1, MAOB, MAOA | LMNA 1714/4885ALOX15 46/4885HTT 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.