Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | JUN | P05412 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744921 | 0.86 | AKR1B10 (0.46) | MAPTLMNANFKB1JUNNFE2L2 | |
| SCHEMBL28658531 | 0.85 | ALDH1A1 (0.47) | MAPTLMNAALOX5KDM4ERAB9A | |
| SCHEMBL28658533 | 0.85 | ALDH1A1 (0.47) | MAPTLMNAALOX5KDM4ERAB9A | |
| SCHEMBL2391128 | 0.83 | MAPT (0.59) | MAPTLMNANFKB1JUNNFE2L2 | |
| SCHEMBL3132306 | 0.83 | MAPT (0.59) | MAPTLMNANFKB1JUNNFE2L2 | |
| SCHEMBL20475031 | 0.82 | NFE2L2 (0.61) | MAPTLMNANFE2L2MAPK1KDM4E | |
| SCHEMBL19901101 | 0.81 | NFKB1 (0.59) | MAPTLMNANFKB1JUNNFE2L2 | |
| SCHEMBL28650877 | 0.80 | ALDH1A1 (0.42) | MAPTLMNAALOX5MAPK1KDM4E | |
| SCHEMBL28650880 | 0.80 | ALDH1A1 (0.42) | MAPTLMNAALOX5MAPK1KDM4E | |
| SCHEMBL11823522 | 0.80 | APP (0.58) | MAPTLMNANFKB1JUNNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160032376-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | IBIS BIOSCIENCES, INC. | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160032376-A1 | NUCLEOTIDE ANALOGS FOR SEQUENCING | RNGTT, POLRMT, NT5C3B | MAPT 3797/4885LMNA 988/4885NFKB1 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.