SCHEMBL17483392

SCHEMBL17483392

N#Cc1c(C#N)c(-c2ccc(N3c4ccccc4Oc4ccccc43)cc2)c(-c2ccccc2)c(-c2ccccc2)c1-c1ccc(N2c3ccccc3Oc3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE9A O76083 1/20 0.38
FAAH O00519 1/20 0.36
MGLL Q99685 1/20 0.36
KDM4E B2RXH2 3/20 0.35
RXFP1 Q9HBX9 1/20 0.35
PTPN1 P18031 1/20 0.35
GRIA4 P48058 5/20 0.35
HPGD P15428 3/20 0.35
GRIA2 P42262 3/20 0.35
AR P10275 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
MAPT P10636 1/20 0.34
TSHR P16473 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
HIF1A Q16665 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17483305 1.00 ALDH1A1 (0.38) ALDH1A1ALOX15HSD17B10PDE9AFAAH
SCHEMBL17483444 0.97 ALDH1A1 (0.33) ALDH1A1ALOX15HSD17B10PDE9AFAAH
SCHEMBL17483338 0.93 ALDH1A1 (0.34) ALDH1A1ALOX15HSD17B10PDE9AFAAH
SCHEMBL17850991 0.88 ALDH1A1 (0.35) ALDH1A1ALOX15HSD17B10PDE9AFAAH
SCHEMBL18932471 0.85 GRIA2 (0.30) GRIA4GRIA2
SCHEMBL23085274 0.84 KDM4E (0.31) ALDH1A1KDM4EGRIA4ARMAPT
SCHEMBL20596630 0.83 PDE9A (0.36) ALDH1A1ALOX15HSD17B10PDE9AKDM4E
SCHEMBL17483443 0.82 PDCD1 (0.35) ALDH1A1KDM4ESMN1; SMN2MAPTLMNA
SCHEMBL13827312 0.81 FAAH (0.47) ALDH1A1ALOX15HSD17B10FAAHMGLL
SCHEMBL18179955 0.81 FAAH (0.47) ALDH1A1ALOX15HSD17B10FAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2021-03-02 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
EP-3093326-B1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND KYULUX INC (JP) 2020-03-18 EP disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2019-11-14 US disclosed
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-08-13 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
EP-3093326-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND Kyulux, Inc. (JP) 2016-11-16 EP disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-2980877-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 ALDH1A1 2419/4885ALOX15 1381/4885HSD17B10 4493/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 ALDH1A1 2419/4885ALOX15 1381/4885HSD17B10 4493/4885
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND CRY2, NR2E3, CRY1 ALDH1A1 391/4885ALOX15 1137/4885HSD17B10 1072/4885
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound CRY1, CRY2, GLB1 ALDH1A1 307/4885ALOX15 1211/4885HSD17B10 1250/4885
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound CRY2, NR2E3, CRY1 ALDH1A1 391/4885ALOX15 1137/4885HSD17B10 1072/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA ALDH1A1 269/4885ALOX15 298/4885HSD17B10 936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.