SCHEMBL17483443

SCHEMBL17483443

N#Cc1c(-c2ccc(N3c4ccccc4Oc4ccccc43)cc2)ccc(-c2ccc(N3c4ccccc4Oc4ccccc43)cc2)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 7/20 0.35
CD274 Q9NZQ7 7/20 0.35
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PIM1 P11309 2/20 0.33
P2RX4 Q99571 2/20 0.33
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
MAPT P10636 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17850974 0.87 PDCD1 (0.30) PDCD1CD274
SCHEMBL17483338 0.86 ALDH1A1 (0.34) KDM4EALDH1A1SMN1; SMN2P2RX4MAPT
SCHEMBL17483444 0.85 ALDH1A1 (0.33) KDM4EALDH1A1SMN1; SMN2PIM1P2RX4
SCHEMBL29512218 0.84 LMNA (0.35) KDM4EALDH1A1SMN1; SMN2P2RX4LMNA
SCHEMBL17483438 0.84 LMNA (0.35) KDM4EALDH1A1SMN1; SMN2P2RX4LMNA
SCHEMBL17883162 0.84 CNR1 (0.36) KDM4EALDH1A1SMN1; SMN2P2RX4LMNA
SCHEMBL17955070 0.84 ESR2 (0.49) ALDH1A1MAPK1
SCHEMBL17483305 0.82 ALDH1A1 (0.38) KDM4EALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL17483392 0.82 ALDH1A1 (0.38) KDM4EALDH1A1SMN1; SMN2LMNAMAPT
SCHEMBL19270815 0.82 PGR (0.40) ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3171421-B1 ORGANIC LIGHT-EMITTING ELEMENT UNIV KYUSHU NAT UNIV CORP (JP) 2023-01-25 EP disclosed
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2021-03-02 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
EP-3706182-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kyushu University National University Corporation (JP) 2020-09-09 EP disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
EP-3093326-B1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND KYULUX INC (JP) 2020-03-18 EP disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND KYULUX, INC. (JP) 2019-11-14 US disclosed
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound KYULUX, INC. (JP) 2019-08-13 US disclosed
EP-2980877-B1 ORGANIC ELECTROLUMINESCENT ELEMENT KYULUX INC (JP) 2017-11-29 EP disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
EP-3171421-A1 ORGANIC LIGHT-EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2017-05-24 EP disclosed
EP-3093326-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING ELEMENT, AND COMPOUND Kyulux, Inc. (JP) 2016-11-16 EP disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
EP-2980877-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Kyushu University, National University Corporation (JP) 2016-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 PDCD1 3724/4885CD274 2488/4885KDM4E 3804/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 PDCD1 3724/4885CD274 2488/4885KDM4E 3804/4885
US-20190345095-A1 LIGHT-EMITTING MATERIAL, ORGANIC LIGHT-EMITTING DEVICE, AND COMPOUND CRY2, NR2E3, CRY1 PDCD1 2858/4885CD274 1623/4885KDM4E 3930/4885
US-10381573-B2 Light-emitting material, organic light-emitting device, and compound CRY1, CRY2, GLB1 PDCD1 2798/4885CD274 1883/4885KDM4E 4226/4885
US-10934248-B2 Light-emitting material, organic light-emitting device, and compound CRY2, NR2E3, CRY1 PDCD1 2858/4885CD274 1623/4885KDM4E 3930/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA PDCD1 1668/4885CD274 1128/4885KDM4E 2784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.