Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1749871 | 0.75 | GAA (0.35) | GAAKDM4EGLAMAPT | |
| SCHEMBL17361676 | 0.69 | KDM4E (0.37) | SLC6A2SLC6A4SLC6A3GAAKDM4E | |
| SCHEMBL30558382 | 0.69 | KDM4E (0.37) | SLC6A2SLC6A4SLC6A3GAAKDM4E | |
| SCHEMBL3984863 | 0.67 | KDM4E (0.42) | GAAKDM4EGLAALDH1A1MAPT | |
| SCHEMBL283021 | 0.66 | GABRA1 (0.46) | GAAKDM4EGLAALDH1A1MAPT | |
| SCHEMBL13610131 | 0.66 | KDM4E (0.45) | GAAKDM4EGLAALDH1A1MAPT | |
| SCHEMBL6264184 | 0.66 | GAA (0.52) | GAATAAR1HTR2ALMNAKDM4E | |
| SCHEMBL1749872 | 0.66 | GAA (0.35) | GAAKDM4EGLAMAPT | |
| SCHEMBL10407969 | 0.65 | GAA (0.36) | GAAHTR2AHTR2CKDM4EGLA | |
| SCHEMBL2015924 | 0.64 | KDM4E (0.39) | GAAHTR2ALMNACYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8710093-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE Ludwigshafen (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2666772-A1 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20110207941-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH | 2011-08-25 | — | — | US | disclosed |
| US-7968730-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | CIBA CORPORATION | 2006-03-16 | — | — | US | disclosed |
| EP-1572647-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Ciba SC Holding AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056769-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | SLC6A2 142/4885SLC6A4 152/4885SLC6A3 716/4885 |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | PNMT, HNMT, MAOA | SLC6A2 120/4885SLC6A4 97/4885SLC6A3 548/4885 |
| US-20110207941-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | SLC6A2 142/4885SLC6A4 152/4885SLC6A3 716/4885 |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | SLC6A2 142/4885SLC6A4 152/4885SLC6A3 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.