Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984863 | 0.68 | KDM4E (0.42) | GAAKDM4EGLAAAK1MAPT | |
| SCHEMBL13610131 | 0.67 | KDM4E (0.45) | GAAKDM4EGLAMAPTPOLB | |
| SCHEMBL283021 | 0.67 | GABRA1 (0.46) | GAAKDM4EGLAMAPTPOLB | |
| SCHEMBL1749871 | 0.67 | GAA (0.35) | GAAKDM4EGLAAAK1MAPT | |
| SCHEMBL10407969 | 0.66 | GAA (0.36) | GAAKDM4EGLAMAPTPOLB | |
| SCHEMBL1749869 | 0.66 | SLC6A2 (0.36) | GAAKDM4EGLAMAPT | |
| SCHEMBL2015924 | 0.65 | KDM4E (0.39) | GAAKDM4EGLAMAPTPOLB | |
| SCHEMBL249883 | 0.65 | HPGD (0.41) | GAAKDM4EGLAMAPTPOLB | |
| SCHEMBL31277331 | 0.65 | CCR2 (0.37) | — | |
| SCHEMBL29268625 | 0.64 | KDM4E (0.42) | GAAKDM4EGLAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8710093-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE Ludwigshafen (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2666772-A1 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20110207941-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH | 2011-08-25 | — | — | US | disclosed |
| US-7968730-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2011-06-28 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | CIBA CORPORATION | 2006-03-16 | — | — | US | disclosed |
| EP-1572647-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Ciba SC Holding AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056769-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | GAA 1047/4885KDM4E 396/4885GLA 1456/4885 |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | PNMT, HNMT, MAOA | GAA 704/4885KDM4E 332/4885GLA 1144/4885 |
| US-20110207941-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | GAA 1047/4885KDM4E 396/4885GLA 1456/4885 |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | GAA 1047/4885KDM4E 396/4885GLA 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.