Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.63 |
| ▸ | HTR2A | P28223 | 5/20 | 0.63 |
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | MPO | P05164 | 2/20 | 0.63 |
| ▸ | HTR1D | P28221 | 10/20 | 0.62 |
| ▸ | HTR1B | P28222 | 8/20 | 0.62 |
| ▸ | HTR2B | P41595 | 4/20 | 0.60 |
| ▸ | HTR7 | P34969 | 4/20 | 0.60 |
| ▸ | HTR5A | P47898 | 4/20 | 0.60 |
| ▸ | HTR6 | P50406 | 4/20 | 0.60 |
| ▸ | HTR1E | P28566 | 3/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.60 |
| ▸ | HTR3B | O95264 | 2/20 | 0.60 |
| ▸ | HTR1F | P30939 | 2/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.60 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.60 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750005 | 0.86 | HTR1A (0.63) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL13227642 | 0.86 | MPO (0.68) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| Hydrochloric Acid SCHEMBL2990516 | 0.84 | HTR1A (0.62) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL2998088 | 0.82 | HTR1A (0.59) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL4226140 | 0.81 | HTR1A (0.68) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL4055413 | 0.79 | HTR1A (0.70) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL29633081 | 0.79 | HTR1A (0.70) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL25380394 | 0.78 | SLC6A4 (0.83) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| Bufotenine SCHEMBL518028 | 0.78 | HTR2C (1.00) | HTR1ASLC6A4HTR2AHTR2CMPO | |
| SCHEMBL1750785 | 0.78 | SLC6A4 (0.83) | HTR1ASLC6A4HTR2AHTR2CMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-1572647-B1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2016-09-21 | — | — | EP | disclosed |
| CN-1729174-B | The synthesis of amine and the intermediate for the synthesis of amine | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2015-10-21 | — | — | CN | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8822702-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2014-09-02 | — | — | US | disclosed |
| US-8710093-B2 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE Ludwigshafen (DE) | 2014-04-29 | — | — | US | disclosed |
| EP-2666772-A1 | Synthesis of amines and intermediates for the synthesis thereof | BASF SE (DE) | 2013-11-27 | — | — | EP | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BERENS ULRICH (DE) | 2012-08-30 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | BASF SE (DE) | 2010-04-08 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-7645886-B2 | Synthesis of amines and intermediates for the synthesis thereof | Ciba Specialty Corporation (US) | 2010-01-12 | — | — | US | disclosed |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | CIBA CORPORATION | 2006-03-16 | — | — | US | disclosed |
| CN-1729174-A | Synthesis of amines and intermediates for the synthesis thereof | CIBA SC HOLDING AG (CH) | 2006-02-01 | — | — | CN | disclosed |
| EP-1572647-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | Ciba SC Holding AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056769-A2 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087660-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | HTR1A 19/4885SLC6A4 152/4885HTR2A 14/4885 |
| US-20060058367-A1 | Synthesis of amines and intermediates for the synthesis thereof | PNMT, HNMT, MAOA | HTR1A 18/4885SLC6A4 97/4885HTR2A 16/4885 |
| US-20120220782-A1 | SYNTHESIS OF AMINES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF | PNMT, HNMT, SMS | HTR1A 19/4885SLC6A4 152/4885HTR2A 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.