SCHEMBL17535

SCHEMBL17535

CCC1(C(=O)OC)CCC1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.52
CYP4A11 Q02928 1/20 0.52
NPSR1 Q6W5P4 1/20 0.42
CETP P11597 1/20 0.36
LMNA P02545 1/20 0.33
P2RX7 Q99572 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.32
CYP3A4 P08684 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MME P08473 1/20 0.31
EPHX1 P07099 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17155 0.95 CYP4F2 (0.56) CYP4F2CYP4A11NPSR1CETPLMNA
SCHEMBL17857 0.93 CYP4F2 (0.55) CYP4F2CYP4A11NPSR1CETPLMNA
SCHEMBL2285823 0.91
SCHEMBL5271625 0.83 CYP4F2 (0.58) CYP4F2CYP4A11NPSR1CETPLMNA
SCHEMBL3952155 0.82 CYP4F2 (0.56) CYP4F2CYP4A11NPSR1LMNAP2RX7
SCHEMBL16310454 0.81 OPRM1 (0.42) CYP4F2CYP4A11NPSR1LMNAKMT2A
SCHEMBL21963873 0.81 CYP4F2 (0.40) CYP4F2CYP4A11NPSR1LMNAMAPT
SCHEMBL16508916 0.81 CYP3A4 (0.40) CYP4F2CYP4A11NPSR1MEN1CYP3A4
SCHEMBL2289682 0.80 SMN1; SMN2 (0.44) LMNAMEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL15572190 0.80 CYP4F2 (0.50) CYP4F2CYP4A11NPSR1LMNAP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025056065-A1 CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE 上海医药集团股份有限公司 2025-03-20 WO disclosed
CN-119638669-A Chemokine receptor antagonist, pharmaceutical composition and application 上海医药集团股份有限公司 2025-03-18 CN disclosed
US-20230150989-A1 HERBICIDAL MALONAMIDES BASF SE (DE) 2023-05-18 US disclosed
US-20180022732-A1 COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO RET BLUEPRINT MEDICINES CORPORATION 2018-01-25 US disclosed
US-20180022736-A1 CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF InventisBio Co., Ltd. (CN) 2018-01-25 US disclosed
US-9809580-B2 Carboxylic acid compound, method for preparation thereof, and use thereof INVENTISBIO SHANGHAI LTD. (CN) 2017-11-07 US disclosed
US-20170233376-A1 CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF InventisBio Co., Ltd. (CN) 2017-08-17 US disclosed
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed
WO-2012025857-A1 CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS HETERO RESEARCH FOUNDATION (IN) 2012-03-01 WO disclosed
US-20110294780-A1 SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-12-01 US disclosed
EP-2179651-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2010-04-28 EP disclosed
EP-2174931-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-04-14 EP disclosed
US-20100069499-A1 AMIDE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-03-04 US disclosed
EP-2151431-A1 AMIDE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2010-02-10 EP disclosed
EP-2143709-A1 AMIDE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2010-01-13 EP disclosed
US-7572783-B2 Obesity; N-(1-benzyl-piperidin-4-yl)-2-(2,5-dioxo-7-phenoxy-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl)-3-methyl-butyramide; modulators of ghrelin receptor (GHSR) AMGEN INC. (US) 2009-08-11 US disclosed
EP-1784390-A2 SUBSTITUTED BENZOFUSED HETEROCYCLES Amgen Inc. (US) 2007-05-16 EP disclosed
US-20060199796-A1 Substituted benzofused heterocycles AMGEN INC. (US) 2006-09-07 US disclosed
WO-2006020959-A2 SUBSTITUTED BENZOFUSED HETEROCYCLES AMGEN INC. (US) 2006-02-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF NAT1, AGXT, HAX1 CYP4F2 1238/4885CYP4A11 1152/4885NPSR1 3041/4885
US-20100069499-A1 AMIDE COMPOUND AND USE THEREOF CBR1, CBR3, GBA1 CYP4F2 403/4885CYP4A11 75/4885NPSR1 1735/4885
US-20180022732-A1 COMPOUNDS USEFUL FOR TREATING DISORDERS RELATED TO RET RET, EYA2, HRAS CYP4F2 4133/4885CYP4A11 4343/4885NPSR1 3401/4885
US-20170233376-A1 CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF CA7, CYP2C9, CA9 CYP4F2 46/4885CYP4A11 24/4885NPSR1 1344/4885
US-20230150989-A1 HERBICIDAL MALONAMIDES DDT, DHRS9, CA9 CYP4F2 386/4885CYP4A11 671/4885NPSR1 3806/4885
US-20060199796-A1 Substituted benzofused heterocycles GPR119, SDHA, OGDH CYP4F2 15/4885CYP4A11 312/4885NPSR1 489/4885
US-20110294780-A1 SUBSTITUTED THIAZOLIDINEDIONE INDAZOLES, INDOLES AND BENZOTRIAZOLES AS ESTROGEN-RELATED RECEPTOR-a MODULATORS ESR2, IGF1R, ESRRA CYP4F2 2242/4885CYP4A11 283/4885NPSR1 2645/4885
US-20180022736-A1 CARBOXYLIC ACID COMPOUND, METHOD FOR PREPARATION THEREOF, AND USE THEREOF CA7, CYP2C9, CA9 CYP4F2 46/4885CYP4A11 24/4885NPSR1 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.