Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RNF4 | P78317 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536300 | 0.76 | HPGD (0.47) | ALDH1A1HTTPAX8HPGDMAPT | |
| SCHEMBL17536328 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HTTSMN1; SMN2PAX8MAPT | |
| SCHEMBL17536308 | 0.71 | HCRTR1 (0.38) | ALDH1A1HTTSMN1; SMN2PAX8HPGD | |
| SCHEMBL3604278 | 0.70 | POLB (0.42) | HTTSMN1; SMN2KEAP1NFE2L2MEN1 | |
| SCHEMBL8809964 | 0.69 | KMT2A (0.43) | ALDH1A1HTTSMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL2205243 | 0.68 | LMNA (0.48) | ALDH1A1HTTSMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL17536294 | 0.68 | ALDH1A1 (0.38) | ALDH1A1HTTSMN1; SMN2PAX8MAPT | |
| SCHEMBL14925281 | 0.66 | KMT2A (0.46) | ALDH1A1HTTSMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL17536348 | 0.66 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2PAX8MEN1 | |
| SCHEMBL11701062 | 0.66 | PAX8 (0.44) | ALDH1A1HTTSMN1; SMN2PAX8HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469617-B2 | Molecules having certain pesticidal utilities, and intermediates, compositions, and processes related thereto | DOW AGROSCIENCES LLC (US) | 2016-10-18 | — | — | US | disclosed |
| US-20160060233-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060233-A1 | MOLECULES HAVING CERTAIN PESTICIDAL UTILITIES, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES RELATED THERETO | ACHE, DDT, MLYCD | ALDH1A1 238/4885HTT 4155/4885SMN1; SMN2 3702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.