Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 7/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27003670 | 0.88 | PRMT3 (0.40) | ALDH1A1HPGDPRMT3CARM1PRMT6 | |
| SCHEMBL15459518 | 0.86 | ALDH1A1 (0.44) | ALDH1A1HPGDPRMT3CARM1PRMT6 | |
| SCHEMBL1834944 | 0.80 | LMNA (0.38) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL23487563 | 0.78 | ALDH1A1 (0.40) | PAOXS1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL18947415 | 0.78 | PRMT3 (0.32) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL6123949 | 0.78 | PAOX (0.34) | PAOXALDH1A1HPGDPRMT3CARM1 | |
| SCHEMBL23487565 | 0.77 | ALDH1A1 (0.42) | RENALDH1A1HPGD | |
| SCHEMBL260446 | 0.76 | ALDH1A1 (0.33) | ALDH1A1PRMT3CARM1PRMT6PRMT1 | |
| SCHEMBL17548968 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4AKDM4C | |
| SCHEMBL13657716 | 0.75 | PAOX (0.39) | PAOXALDH1A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9910190-B2 | Poly(oxazoline-co-ethyleneimine)-epichlorohydrin copolymers and uses thereof | NOVARTIS AG (CH) | 2018-03-06 | — | — | US | disclosed |
| US-20170293050-A1 | POLY(OXAZOLINE-CO-ETHYLENEIMINE)-EPICHLOROHYDRIN COPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2017-10-12 | — | — | US | disclosed |
| US-9720138-B2 | Poly(oxazoline-co-ethyleneimine)-epichlorohydrin copolymers and uses thereof | NOVARTIS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20160061995-A1 | POLY(OXAZOLINE-CO-ETHYLENEIMINE)-EPICHLOROHYDRIN COPOLYMERS AND USES THEREOF | ALCON INC. (CH) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160061995-A1 | POLY(OXAZOLINE-CO-ETHYLENEIMINE)-EPICHLOROHYDRIN COPOLYMERS AND USES THEREOF | EPN1, PAM, LAGE3 | PAOX 1117/4885S1PR2 4332/4885S1PR1 4607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.