Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.37 |
| ▸ | GRB2 | P62993 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553512 | 0.94 | MMP1 (0.40) | PTPN1RENPAX8TDP1TLR2 | |
| SCHEMBL17553508 | 0.87 | CCKAR (0.38) | — | |
| SCHEMBL17553607 | 0.86 | ALDH1A1 (0.38) | — | |
| SCHEMBL17553585 | 0.84 | CASP3 (0.42) | PTPN1 | |
| SCHEMBL17553573 | 0.82 | MMP1 (0.39) | PTPN1GRB2PAX8TDP1TLR2 | |
| SCHEMBL17553448 | 0.81 | MMP1 (0.38) | PTPN1GRB2PAX8TDP1TLR2 | |
| SCHEMBL17553675 | 0.81 | REN (0.44) | RENPAX8TDP1 | |
| SCHEMBL17553572 | 0.80 | MMP1 (0.43) | PTPN1GRB2RENPAX8TDP1 | |
| SCHEMBL17553513 | 0.80 | MMP1 (0.46) | RENPAX8TDP1 | |
| SCHEMBL23922657 | 0.78 | MDM2 (0.48) | PTPN1RENPAX8TDP1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |