Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 4/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553670 | 0.88 | CTSL (0.47) | CTSL | |
| SCHEMBL17553674 | 0.83 | ALDH1A1 (0.44) | RENTDP1CTSLPSMB5ALDH1A1 | |
| SCHEMBL17553669 | 0.81 | PTPN1 (0.37) | RENPAX8TDP1 | |
| SCHEMBL17553513 | 0.81 | MMP1 (0.46) | RENPAX8TDP1PSMB8PSMB9 | |
| SCHEMBL12285382 | 0.80 | PAX8 (0.51) | PAX8TDP1CTSLPSMB8PSMB9 | |
| SCHEMBL17553671 | 0.80 | MMP1 (0.46) | RENPAX8TDP1PSMB8PSMB9 | |
| SCHEMBL17553615 | 0.79 | ALDH1A1 (0.48) | CTSLALDH1A1CA2 | |
| SCHEMBL20653746 | 0.79 | CTSL (0.67) | RENPAX8TDP1CTSLPSMB8 | |
| SCHEMBL8259105 | 0.78 | CTSS (0.50) | PAX8TDP1CTSLPSMB8PSMB9 | |
| SCHEMBL17553451 | 0.78 | CCKBR (0.40) | RENPAX8TDP1PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |