Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553513 | 0.83 | MMP1 (0.46) | MMP1MMP3MMP9TDP1PAX8 | |
| SCHEMBL12285382 | 0.81 | PAX8 (0.51) | TDP1PAX8PSMB8PSMB9PSMB5 | |
| SCHEMBL17553573 | 0.81 | MMP1 (0.39) | MMP1MMP3MMP9TDP1PAX8 | |
| SCHEMBL8259105 | 0.80 | CTSS (0.50) | TDP1PAX8PSMB8PSMB9PSMB5 | |
| SCHEMBL17553675 | 0.80 | REN (0.44) | TDP1PAX8PSMB8PSMB9PSMB5 | |
| SCHEMBL17553664 | 0.79 | ALDH1A1 (0.48) | ALDH1A1 | |
| SCHEMBL17553672 | 0.79 | MMP1 (0.42) | MMP1MMP3MMP9TDP1PAX8 | |
| SCHEMBL12285414 | 0.78 | PSMB8 (0.47) | TDP1PAX8PSMB8PSMB9PSMB5 | |
| SCHEMBL5303063 | 0.78 | MAPT (0.51) | MMP1MMP3MMP9TDP1PAX8 | |
| SCHEMBL8243065 | 0.78 | MAPT (0.51) | MMP1MMP3MMP9TDP1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |