Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553615 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CTSKCASP1CA12CA2 | |
| SCHEMBL17553666 | 0.90 | CTSK (0.55) | CTSKCA12CA2CA7CA9 | |
| SCHEMBL17553675 | 0.83 | REN (0.44) | ALDH1A1CA2PSMB5CTSLTDP1 | |
| SCHEMBL17553668 | 0.83 | PTPN1 (0.43) | CTSKATM | |
| SCHEMBL17553670 | 0.80 | CTSL (0.47) | CTSL | |
| SCHEMBL17553583 | 0.79 | CTSS (0.42) | ALDH1A1CTSKCASP1CA12CA7 | |
| SCHEMBL17553607 | 0.76 | ALDH1A1 (0.38) | ALDH1A1CTSKCASP1CTSSCTSL | |
| SCHEMBL1509254 | 0.75 | CTSK (0.57) | CTSKCTSSCTSLCTSBCAPN1 | |
| SCHEMBL30065139 | 0.74 | CTSS (0.60) | ALDH1A1CTSKCTSSCTSLCTSB | |
| SCHEMBL22398511 | 0.74 | CA12 (0.61) | CTSKCA12CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029324-A1 | AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF | RSEM, LIMITED PARTNERSHIP (CA) | 2016-03-03 | — | — | WO | disclosed |