SCHEMBL1756074

SCHEMBL1756074

CC(C)(S)CC(=O)OCCCCOC(=O)CC(C)(C)S

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.43
RAD52 P43351 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
FAAH O00519 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
HTR2C P28335 1/20 0.35
DGKA P23743 1/20 0.34
ALDH1A1 P00352 2/20 0.33
POLB P06746 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
EPHX1 P07099 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA1A P35348 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL869221 0.91 DGKA (0.37) NAAATDP1DGKAALDH1A1ADRA2A
SCHEMBL23198173 0.86 NAAA (0.34) NAAARAD52NPSR1MEN1KMT2A
SCHEMBL28150175 0.86 NAAA (0.38) NAAARAD52NPSR1FAAHTDP1
SCHEMBL19433047 0.84 ALDH1A1 (0.35) DGKAALDH1A1ADRA2AADRA1ATSHR
SCHEMBL10074407 0.83 NAAA (0.33) NAAATDP1
SCHEMBL27968609 0.79 GAA (0.50) ALDH1A1HTT
SCHEMBL869482 0.77 MAPK1 (0.32)
SCHEMBL8374682 0.75 ALDH1A1 (0.38) ALDH1A1ADRA1ATSHR
SCHEMBL28463776 0.75 NAAA (0.62) NAAARAD52NPSR1FAAHHTR2C
SCHEMBL20734718 0.75 GAA (0.41) NPSR1TDP1ALDH1A1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150080509-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL NITTA GELATIN KK (JP) 2015-03-19 US disclosed
US-20150080509-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL NITTA GELATIN KK (JP) 2015-03-19 US disclosed
US-8921446-B2 Photocurable material for sealing, sealing method, sealing material, and housing using said sealing material NITTA GELATIN INC. (JP) 2014-12-30 US disclosed
US-8921446-B2 Photocurable material for sealing, sealing method, sealing material, and housing using said sealing material NITTA GELATIN INC. (JP) 2014-12-30 US disclosed
US-20130303651-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL BOSTIK SA (FR) 2013-11-14 US disclosed
US-20130303651-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL BOSTIK SA (FR) 2013-11-14 US disclosed
EP-1983017-B1 CURABLE COMPOSITION CONTAINING THIOL COMPOUND SHOWA DENKO KK (JP) 2012-04-18 EP disclosed
US-7888399-B2 Curable composition containing thiol compound SHOWA DENKO K.K. (JP) 2011-02-15 US disclosed
US-7888399-B2 Curable composition containing thiol compound SHOWA DENKO K.K. (JP) 2011-02-15 US disclosed
US-20100210812-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2010-08-19 US disclosed
US-20100210812-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2010-08-19 US disclosed
US-20100087611-A1 URETHANE COMPOUND, CURABLE COMPOSITION CONTAINING THE SAME, AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2010-04-08 US disclosed
US-20100087611-A1 URETHANE COMPOUND, CURABLE COMPOSITION CONTAINING THE SAME, AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2010-04-08 US disclosed
EP-2172509-A1 CURABLE COMPOSITION AND CURED PRODUCT THEREOF Showa Denko K.K. (JP) 2010-04-07 EP disclosed
EP-2143739-A1 URETHANE COMPOUND, CURABLE COMPOSITION CONTAINING THE SAME, AND CURED PRODUCT OF THE COMPOSITION Showa Denko K.K. (JP) 2010-01-13 EP disclosed
US-20090023831-A1 Curable Composition Containing Thiol Compound SHOWA DENKO K.K. (JP) 2009-01-22 US disclosed
US-20090023831-A1 Curable Composition Containing Thiol Compound SHOWA DENKO K.K. (JP) 2009-01-22 US disclosed
EP-1983017-A1 CURABLE COMPOSITION CONTAINING THIOL COMPOUND Showa Denko K.K. (JP) 2008-10-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087611-A1 URETHANE COMPOUND, CURABLE COMPOSITION CONTAINING THE SAME, AND CURED PRODUCT THEREOF ITCH, GLI1, UNC119 NAAA 1803/4885RAD52 1488/4885NPSR1 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.