Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4570259 | 0.77 | PRKCA (0.37) | PRKCADGKA | |
| SCHEMBL1835849 | 0.72 | MGLL (0.36) | PRKCADGKA | |
| SCHEMBL3598138 | 0.70 | CYP1A2 (0.42) | RAB9AL3MBTL1LMNAPOLBALDH1A1 | |
| SCHEMBL4570257 | 0.69 | CTDSP1 (0.36) | PRKCA | |
| SCHEMBL1816515 | 0.68 | ADRA2A (0.48) | DGKA | |
| SCHEMBL4570260 | 0.67 | ADRA2A (0.45) | LMNADGKAALDH1A1 | |
| SCHEMBL2353637 | 0.66 | DGKA (0.48) | L3MBTL1POLBSMN1; SMN2DGKAALDH1A1 | |
| SCHEMBL749774 | 0.66 | DGKA (0.54) | L3MBTL1LMNAPOLBSMN1; SMN2DGKA | |
| SCHEMBL3504167 | 0.66 | DGKA (0.43) | DGKA | |
| Dioxane SCHEMBL3709090 | 0.66 | LMNA (0.38) | PRKCARAB9AL3MBTL1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840607-B2 | Polyhydroxy ketal ester adducts, methods of manufacture and uses thereof | GFBIOCHEMICALS LIMITED (MT) | 2017-12-12 | — | — | US | disclosed |
| US-9840607-B2 | Polyhydroxy ketal ester adducts, methods of manufacture and uses thereof | GFBIOCHEMICALS LIMITED (MT) | 2017-12-12 | — | — | US | disclosed |
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | GFBIOCHEMICALS LIMITED (MT) | 2016-03-10 | — | — | US | disclosed |
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | GFBIOCHEMICALS LIMITED (MT) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068660-A1 | POLYHYDROXY KETAL ESTER ADDUCTS, METHODS OF MANUFACTURE AND USES THEREOF | ALKBH3, PHYKPL, KYAT1 | PRKCA 680/4885RAB9A 4473/4885L3MBTL1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.