SCHEMBL2167285

SCHEMBL2167285

Cc1ccc(C(=O)c2ccccc2O)c(O)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.62
HPGD P15428 2/20 0.62
CYP1A2 P05177 1/20 0.62
PGR P06401 1/20 0.62
CYP3A4 P08684 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
AR P10275 1/20 0.62
CHRM1 P11229 1/20 0.62
ALOX15 P16050 1/20 0.62
TBXA2R P21731 1/20 0.62
SLC6A2 P23975 1/20 0.62
CYP2C19 P33261 1/20 0.62
ADRA1A P35348 1/20 0.62
HIF1A Q16665 1/20 0.62
SPR P35270 1/20 0.56
IDO1 P14902 2/20 0.54
TDO2 P48775 2/20 0.54
GSTA1 P08263 2/20 0.53
RAB9A P51151 6/20 0.53
HSD17B10 Q99714 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578000 0.90 NPC1 (0.56) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL1758035 0.90 NPC1 (0.56) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL12909853 0.89 ALDH1A1 (0.51) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL9717038 0.89 LMNA (0.54) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL5962983 0.89 GSTA1 (0.62) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL15761520 0.87 IDO1 (0.50) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL12325927 0.87 ALDH1A1 (0.68) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL144223 0.86 KMT2A (0.57) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL20404612 0.84 IDO1 (0.51) LMNAHPGDCYP1A2PGRCYP3A4
SCHEMBL14259809 0.84 RAB9A (0.69) LMNAHPGDIDO1TDO2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765334-B2 Protective photoreceptor outer layer XEROX CORPORATION (US) 2014-07-01 US disclosed
US-8293150-B2 Near-infrared absorbing material FUJIFILM CORPORATION (JP) 2012-10-23 US disclosed
US-20110183241-A1 PROTECTIVE PHOTORECEPTOR OUTER LAYER XEROX CORPORATION (US) 2011-07-28 US disclosed
US-7875215-B2 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2011-01-25 US disclosed
US-20100285293-A1 MULTIFUNCTIONAL ADHESIVE FILM, PLASMA DISPLAY PANEL FILTER CONTAINING THE SAME AND PLASMA DISPLAY PANEL CONTAINING THE SAME LG CHEM, LTD. (KR) 2010-11-11 US disclosed
US-20100224839-A1 NEAR-INFRARED ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2010-09-09 US disclosed
US-7687229-B2 Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORPORATION (JP) 2010-03-30 US disclosed
US-20090117266-A1 NEAR-INFRARED-ABSORBING MATERIAL FUJIFILM CORPORATION (JP) 2009-05-07 US disclosed
EP-1505412-B1 Plastic lens and process for producing the lens HOYA CORP (JP) 2008-11-05 EP disclosed
US-20080169453-A1 Near infrared ray absorbing material and near infrared ray absorbing filter FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20080073626-A1 A singlet oxygen scavenger, a radical trapping agent and an antioxidant; quaternary or amine salt derivatives of 4-hydroxy-3-cyclopenten-1,-2-dione; discoloration inhibition, light resistance; electrooptics, liquid crystal display, optical cards, optical recording media, and protective goggles FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 US disclosed
US-4305839-A PHOSPHITES AND PHOSPHONITES FOR COLOR STABILITY CARSTAB CORPORATION (US) 1981-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080169453-A1 Near infrared ray absorbing material and near infrared ray absorbing filter RRP12, MRPS22, H1-10 LMNA 1943/4885HPGD 3181/4885CYP1A2 693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.