Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5543471 | 0.79 | MAPK1 (0.51) | MAPTMAPK1KMT2ALMNAEGFR | |
| SCHEMBL15283252 | 0.75 | ADRA2C (0.58) | MAPTMAPK1KMT2ALMNAEGFR | |
| SCHEMBL15283314 | 0.73 | ALK (0.42) | ALKMAPTMAPK1KMT2ALMNA | |
| SCHEMBL15283799 | 0.73 | MAPT (0.46) | MAPTKMT2ALMNAALDH1A1DRD2 | |
| SCHEMBL17580475 | 0.72 | HTR6 (0.44) | MAPTMAPK1ALDH1A1POLBTDP1 | |
| SCHEMBL15283283 | 0.72 | EGFR (0.42) | ALKMAPTEGFRALDH1A1DRD2 | |
| SCHEMBL17580393 | 0.71 | UCHL3 (0.49) | ALKMAPTMAPK1ALDH1A1 | |
| SCHEMBL14621895 | 0.68 | DRD2 (0.67) | DRD2DRD3HTR1ADRD4ADRA2C | |
| SCHEMBL17580638 | 0.68 | LMNA (0.42) | ALKMAPTLMNAEGFRALDH1A1 | |
| SCHEMBL17580551 | 0.68 | HTR3A (0.40) | EGFRDRD2DRD3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834248-B1 | NOVEL THIENOPYRIMIDINE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI SA (FR) | 2016-03-16 | — | — | EP | disclosed |