Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SGK1 | O00141 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17599337 | 0.85 | PTK2B (0.50) | KMT2AMEN1GAAG6PDMAP1LC3B | |
| SCHEMBL17599376 | 0.82 | FABP4 (0.56) | KMT2AMEN1GAAG6PDMAP1LC3B | |
| SCHEMBL17599312 | 0.81 | KEAP1 (0.61) | KMT2AMEN1GAAMCL1KDM4E | |
| SCHEMBL17599330 | 0.79 | WDR5 (0.47) | KMT2AMEN1ACLYMCL1KDM4E | |
| SCHEMBL17613351 | 0.79 | KDM4E (0.38) | KMT2AMEN1GAAALDH1A1HPGD | |
| SCHEMBL17599351 | 0.78 | KMT2A (0.45) | KMT2AMEN1SLC16A3ACLYTDP1 | |
| SCHEMBL17599403 | 0.78 | WDR5 (0.49) | KMT2AMEN1L3MBTL1SLC16A3ACLY | |
| SCHEMBL17599404 | 0.77 | KMT2A (0.48) | KMT2AMEN1GAAG6PDL3MBTL1 | |
| SCHEMBL17599371 | 0.77 | KMT2A (0.51) | KMT2AMEN1L3MBTL1SLC16A3ACLY | |
| SCHEMBL17599329 | 0.77 | KMT2A (0.55) | KMT2AMEN1ACLYMCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2998294-A1 | Naphthyl sulfonamide phenyl derivatives as KEAP-1 modulators for the treatment of diabetes, obesity, dyslipidemia and related disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |