SCHEMBL17600548

SCHEMBL17600548

FC(F)(F)C1(c2ccc(CCOCc3ccc(C4(C(F)(F)F)N=N4)cc3)cc2)N=N1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.36
PTPN2 P17706 1/20 0.36
PTPN1 P18031 1/20 0.36
PTPN6 P29350 1/20 0.36
GABRA1 P14867 3/20 0.34
GABRB2 P47870 2/20 0.34
ABCB1 P08183 3/20 0.33
KCNH2 Q12809 1/20 0.33
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NOS1 P29475 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17600538 0.92 KIF11 (0.39) KIF11GABRA1GABRB2ABCB1KCNH2
SCHEMBL19399249 0.92 GABRA1 (0.33) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL17600542 0.91 L3MBTL1 (0.38) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL17642491 0.90 PTPN2 (0.41) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL17642496 0.89 KIF11 (0.37) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL17600537 0.88 KIF11 (0.41) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL24862615 0.88 L3MBTL1 (0.46) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL17642475 0.87 TDP1 (0.37) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL19399244 0.83 L3MBTL1 (0.36) KIF11PTPN2PTPN1PTPN6GABRA1
SCHEMBL19399243 0.83 KIF11 (0.34) KIF11GABRA1GABRB2ABCB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US claimed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP claimed
US-10693072-B2 Diazirine containing organic electronic compositions and device thereof PROMERUS, LLC (US) 2020-06-23 US claimed
EP-3197881-B1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS LLC (US) 2020-04-29 EP claimed
US-10303060-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2019-05-28 US claimed
US-20190157558-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2019-05-23 US claimed
US-10256409-B2 Diazirine containing organic electronic compositions and device thereof PROMERUS, LLC (US) 2019-04-09 US claimed
EP-3433884-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF Promerus, LLC (US) 2019-01-30 EP claimed
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM PROMERUS, LLC (US) 2018-07-05 US claimed
US-9938241-B2 Diazirine compounds and compositions derived therefrom PROMERUS, LLC (US) 2018-04-10 US claimed
US-20170279048-A1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS, LLC (US) 2017-09-28 US claimed
EP-3197881-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM Promerus, LLC (US) 2017-08-02 EP claimed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO claimed
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM SUMITOMO BAKELITE CO., LTD. (JP) 2016-03-24 US claimed
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PROMERUS, LLC (US) 2024-10-10 US disclosed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP disclosed
EP-3433884-B1 DIAZIRINE CONTAINING ORGANIC ELECTRONIC COMPOSITIONS AND DEVICE THEREOF PROMERUS LLC (US) 2023-01-11 EP disclosed
EP-3197881-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM Promerus, LLC (US) 2017-08-02 EP disclosed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO disclosed
WO-2016049123-A1 DIAZIRINE COMPOUNDS AS PHOTOCROSSLINKERS AND PHOTOIMAGEABLE COMPOSITIONS COMPRISING THEM PROMERUS, LLC (US) 2016-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336599-A1 PHOTOSENSITIVE POLYAMIC ACID AND DIAZIRINE COMPOSITIONS PUF60, FTO, PARN KIF11 2032/4885PTPN2 1776/4885PTPN1 2290/4885
US-20160083352-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM RDX, AOX1, ALDH1A2 KIF11 2915/4885PTPN2 1570/4885PTPN1 1344/4885
US-20180186747-A1 DIAZIRINE COMPOUNDS AND COMPOSITIONS DERIVED THEREFROM ZYX, AOX1, RDX KIF11 2025/4885PTPN2 1288/4885PTPN1 1228/4885
US-10303060-B2 Diazirine compounds and compositions derived therefrom ZYX, AOX1, RDX KIF11 2025/4885PTPN2 1288/4885PTPN1 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.