Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.41 |
| ▸ | KDM5A | P29375 | 2/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17604623 | 0.83 | KDM4C (0.62) | PKML3MBTL1KDM4CKDM5APHF8 | |
| SCHEMBL17604625 | 0.83 | KDM4C (0.62) | PKML3MBTL1KDM4CKDM5APHF8 | |
| SCHEMBL17604535 | 0.81 | KDM4C (0.46) | KDM4CKDM5APHF8KDM2BCYP2C9 | |
| SCHEMBL17604575 | 0.80 | PKM (0.42) | PKML3MBTL1KDM4CKDM5APHF8 | |
| SCHEMBL16095596 | 0.77 | KDM4C (0.65) | KDM4CKDM5APHF8KDM2BCYP2C9 | |
| SCHEMBL17604576 | 0.76 | KDM4C (0.47) | KDM4CKDM5APHF8KDM2BMAPK14 | |
| SCHEMBL16095268 | 0.71 | KDM4C (0.45) | L3MBTL1KDM4CMAPK14 | |
| SCHEMBL16095130 | 0.70 | KDM4C (0.69) | KDM4CKDM5APHF8KDM2B | |
| SCHEMBL16102461 | 0.67 | KDM4C (0.42) | KDM4CPHF8MAPK14 | |
| SCHEMBL16095350 | 0.67 | KDM4C (0.67) | KDM4CKDM5AKDM2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193881-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016044342-A1 | HISTONE DEMETHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2016-03-24 | — | — | WO | disclosed |