Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.62 |
| ▸ | LMNA | P02545 | 10/20 | 0.62 |
| ▸ | NPC1 | O15118 | 10/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | HTT | P42858 | 8/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 1/20 | 0.60 |
| ▸ | ALPG | P10696 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704508 | 1.00 | RAB9A (0.62) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL17609266 | 0.80 | NPC1 (0.65) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL17609165 | 0.79 | RIPK1 (0.47) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL29568028 | 0.76 | NPBWR1 (0.73) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL2689294 | 0.76 | NPBWR1 (0.73) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL10860786 | 0.75 | MAPT (0.48) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL7808579 | 0.75 | NPC1 (1.00) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL3334644 | 0.73 | NPBWR1 (0.73) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL1086985 | 0.73 | ALDH1A1 (0.81) | RAB9ALMNANPC1MAPTMEN1 | |
| SCHEMBL29539476 | 0.73 | ALDH1A1 (0.81) | RAB9ALMNANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124770-B2 | Fluorescent cellular markers | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-02-28 | — | — | US | disclosed |
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256378-A1 | FLUORESCENT CELLULAR MARKERS | AIFM1, CASP3, BAX | RAB9A 862/4885LMNA 355/4885NPC1 1894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.