SCHEMBL17622363

SCHEMBL17622363

Nn1c2ccc(N(c3ccccc3)c3ccccc3)cc2c2cc(N(c3ccccc3)c3ccccc3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.47
▸ MAPT P10636 4/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.47
▸ KDM4E B2RXH2 2/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ CYP1A2 P05177 1/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ CYP2D6 P10635 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ CYP2C19 P33261 1/20 0.47
▸ MEN1 O00255 5/20 0.36
▸ KMT2A Q03164 5/20 0.36
▸ ATM Q13315 2/20 0.36
▸ CRHBP P24387 1/20 0.36
▸ CRHR2 Q13324 1/20 0.36
▸ TLR9 Q9NR96 1/20 0.36
▸ APP P05067 2/20 0.32
▸ MAPK1 P28482 3/20 0.32
▸ HPGD P15428 2/20 0.32
▸ HTT P42858 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18388620 0.95 KDM4E (0.42) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL19268911 0.90 KDM4E (0.39) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL19268418 0.85 L3MBTL1 (0.47) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL12559418 0.81 GPR3 (0.45) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL17265851 0.81 ALDH1A1 (0.42) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL23052976 0.81 ALDH1A1 (0.42) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL16696178 0.81 GPR3 (0.45) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL19269318 0.81 MMP3 (0.40) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL19269353 0.80 ESR1 (0.39) ALDH1A1MAPTL3MBTL1KDM4ETDP1
SCHEMBL13301590 0.79 KDM4E (0.50) ALDH1A1MAPTL3MBTL1KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11758809-B2 Compound, display panel, and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-09-12 — — US disclosed
US-11691991-B2 Compound, a display panel and a display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-07-04 — — US disclosed
US-11345689-B2 Compound and organic light emitting display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2022-05-31 — — US disclosed
US-11312710-B2 Compound and organic light-emitting display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2022-04-26 — — US disclosed
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS THE SCRIPPS RESEARCH INSTITUTE 2020-10-08 — — US disclosed
EP-3647392-A1 LIGHT-EMITTING MATERIAL, COMPOUND, LONG-PERSISTENT PHOSPHOR AND LIGHT-EMITTING ELEMENT Kyulux, Inc. (JP) 2020-05-06 — — EP disclosed
US-20190135797-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE Shanghai Tianma AM-OLED Co., Ltd. (CN) 2019-05-09 — — US disclosed
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-24 — — US disclosed
EP-3113239-A1 ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES cynora GmbH (DE) 2017-01-04 — — EP disclosed
WO-2016042070-A1 ORGANIC MOLECULES FOR USE AS EMITTERS CYNORA GMBH (DE) 2016-03-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190135797-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE TEAD2, TEAD4, TEAD1 ALDH1A1 706/4885MAPT 1461/4885L3MBTL1 471/4885
US-11345689-B2 Compound and organic light emitting display device DRD4, NECTIN4, DRD1 ALDH1A1 39/4885MAPT 991/4885L3MBTL1 849/4885
US-11691991-B2 Compound, a display panel and a display device BROX, BRSK1, BRSK2 ALDH1A1 711/4885MAPT 650/4885L3MBTL1 3452/4885
US-20200321533-A1 COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS ALDH1A2, DDT, CLTB ALDH1A1 11/4885MAPT 649/4885L3MBTL1 51/4885
US-20170244049-A1 ORGANIC LIGHT-EMITTING DIODE MATERIALS CYBA, DDT, DRD1 ALDH1A1 19/4885MAPT 640/4885L3MBTL1 24/4885
US-11312710-B2 Compound and organic light-emitting display device TEAD2, TEAD4, TEAD1 ALDH1A1 706/4885MAPT 1461/4885L3MBTL1 471/4885
US-11758809-B2 Compound, display panel, and display apparatus C1S, C3AR1, DRD3 ALDH1A1 928/4885MAPT 4162/4885L3MBTL1 3173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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