Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.34 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 2/20 | 0.30 |
| ▸ | FNTB | P49356 | 2/20 | 0.30 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.30 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.30 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17631644 | 0.80 | CDK9 (0.40) | USP30CDK9TBK1PRKCIPRKD1 | |
| SCHEMBL17631671 | 0.78 | USP30 (0.41) | USP30CDK9 | |
| SCHEMBL17632095 | 0.78 | USP30 (0.41) | USP30CDK9 | |
| SCHEMBL17632283 | 0.73 | MKNK1 (0.38) | CDK9TBK1PRKD1PRKD2 | |
| SCHEMBL17631866 | 0.68 | CDK9 (0.41) | CDK9PRKCI | |
| SCHEMBL17631915 | 0.68 | CDK9 (0.35) | CDK9TBK1 | |
| SCHEMBL17632111 | 0.68 | UCHL1 (0.35) | USP30CDK9 | |
| SCHEMBL17631858 | 0.67 | CDK9 (0.35) | CDK9 | |
| SCHEMBL17632600 | 0.67 | CDK9 (0.39) | CDK9 | |
| SCHEMBL17632617 | 0.66 | CDK9 (0.42) | USP30CDK9PRKD1PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |