Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17632111 | 0.90 | UCHL1 (0.35) | CDK9UCHL1TLR9TLR8TLR7 | |
| SCHEMBL17632095 | 0.79 | USP30 (0.41) | CDK9 | |
| SCHEMBL17631671 | 0.79 | USP30 (0.41) | CDK9 | |
| SCHEMBL17632283 | 0.78 | MKNK1 (0.38) | CDK9TLR9TLR8TLR7 | |
| SCHEMBL17631644 | 0.78 | CDK9 (0.40) | CDK9 | |
| SCHEMBL17631866 | 0.73 | CDK9 (0.41) | CDK9 | |
| SCHEMBL17631915 | 0.73 | CDK9 (0.35) | CDK9 | |
| SCHEMBL17631887 | 0.72 | USP30 (0.44) | UCHL1CTSKCTSC | |
| SCHEMBL17632617 | 0.72 | CDK9 (0.42) | CDK9UCHL1 | |
| SCHEMBL17632787 | 0.71 | MEN1 (0.40) | CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | claimed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | claimed |
| EP-3197883-A1 | NOVEL COMPOUNDS | Mission Therapeutics Limited (GB) | 2017-08-02 | — | — | EP | disclosed |
| WO-2016046530-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LTD (GB) | 2016-03-31 | — | — | WO | disclosed |